IpiRecord: IPI00385215

IPI00385215 - NFATC4, CYTOPLASMIC NUCLEAR FACTOR OF ACTIVATED T-CELLS 4.
Uniprot Accession: Q96H68
Uniprot ID: Q96H68_HUMAN
Mapping: Chr 14, 23907094 - 23918645
Entrez Gene: 4776
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12325)
Rat: Nfatc4, SIMILAR TO CYTOPLASMIC NUCLEAR FACTOR OF ACTIVATED T-CELLS 4.
Mouse: Nfatc4, T-CELLS, CYTOPLASMIC, CALCINEURIN-DEPENDENT 4, FULL INSERT SEQUENCE.
Human: NFATC4, NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 4.
Human: NFATC4, CYTOPLASMIC NUCLEAR FACTOR OF ACTIVATED T-CELLS 4.

Annotations for NFATC4 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCIEA IDA 
cytosolCIMP 
nucleusCIEA IEA IMP IMP 
transcription factor activityFIEA IDA ISS IMP 
transcription coactivator activityFTAS ISS 
catalytic activityFRCA ISS 
DNA bindingFIDA ISS 
metabolic processPRCA ISS 
regulation of synaptic plasticityPIMP 
transcription from RNA polymerase II promoterPTAS ISS 
inflammatory responsePTAS ISS 
heart developmentPIEA IGI ISS 
cellular respirationPIEA IDA ISS 
regulation of transcription, DNA-dependentPIEA IDA ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (11)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
craniofacial phenotypeMPUn
behavior/neurological phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn
skeleton phenotypeMPUn
muscle phenotypeMPUn
nervous system phenotypeMPUn
cardiovascular system phenotypeMPUn
digestive/alimentary phenotypeMPUn
growth/size phenotypeMPUn

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Hypertrophy, Left VentricularDISS
Hypertrophy, Right VentricularDISS
Cardiomyopathy, CongestiveDISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
calcineurin signaling pathwayWISS
nuclear factor of activated T-cells signaling pathwayWISS

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayNot present in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Axon guidance (04360)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway