IpiRecord: IPI00385568

IPI00385568 - LRP1, LRP1 PROTEIN.
Uniprot Accession: Q7Z7K9
Uniprot ID: Q7Z7K9_HUMAN
Mapping: Chr 12, 55808543 - 55893390
Entrez Gene: 4035
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7062)
Rat: Lrp1, SIMILAR TO LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1.
Mouse: Lrp1, PROLOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1 PRECURSOR.
Human: LRP1, PROLOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1 PRECURSOR.
Human: LRP1, LRP1 PROTEIN.
Human: LRP1, LRP1 PROTEIN.
Human: LRP1, 14 KDA PROTEIN.
Human: LRP1, 14 KDA PROTEIN.
Human: LRP1, LRP1 PROTEIN.

Annotations for LRP1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to plasma membraneCTAS ISS 
dendriteCIDA 
membrane fractionCTAS IDA ISS ISS 
membraneCIEA RCA ISS 
clathrin-coated vesicleCIDA 
endosomeCIDA 
integral to membraneCIEA 
nucleusCIEA IEA 
coated pitCIEA IEA 
cell somaCIDA 
cytoplasmCIEA IEA 
plasma membraneCISS 
lipoprotein bindingFTAS ISS 
calcium ion bindingFTAS IEA RCA ISS ISS 
lipid transporter activityFTAS ISS 
metal ion bindingFIEA 
receptor activityFTAS IEA ISS ISS 
protein bindingFIPI IPI IMP 
protein kinase C activationPIMP 
negative regulation of Wnt receptor signaling pathwayPIEA IDA ISS 
positive regulation of anti-apoptosisPIMP 
endocytosisPIEA IEA ISS 
cell proliferationPTAS ISS IMP 
lipoprotein metabolic processPIEP 
multicellular organismal developmentPIEA IEA 
agingPIEP 
lipid metabolic processPTAS ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
lethality-embryonic/perinatalMPUn

Disease (5)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Myocardial InfarctionDISS
ArteriosclerosisDISS
Retinal NeovascularizationDIEP
Prostatic Intraepithelial NeoplasiaDIEP
Coronary DiseaseDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Alzheimer's disease (05010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway