| IPI00385568 - LRP1, LRP1 PROTEIN. | |
|---|---|
| Uniprot Accession: Q7Z7K9 | |
| Uniprot ID: Q7Z7K9_HUMAN | |
| Mapping: Chr 12, 55808543 - 55893390 | |
| Entrez Gene: 4035 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7062) |
|---|
| Rat: Lrp1, SIMILAR TO LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1. |
| Mouse: Lrp1, PROLOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1 PRECURSOR. |
| Human: LRP1, PROLOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1 PRECURSOR. |
| Human: LRP1, LRP1 PROTEIN. |
| Human: LRP1, LRP1 PROTEIN. |
| Human: LRP1, 14 KDA PROTEIN. |
| Human: LRP1, 14 KDA PROTEIN. |
| Human: LRP1, LRP1 PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| integral to plasma membrane | C | TAS | ISS | |
| dendrite | C | IDA | ||
| membrane fraction | C | TAS | IDA | ISS ISS |
| membrane | C | IEA | RCA | ISS |
| clathrin-coated vesicle | C | IDA | ||
| endosome | C | IDA | ||
| integral to membrane | C | IEA | ||
| nucleus | C | IEA | IEA | |
| coated pit | C | IEA | IEA | |
| cell soma | C | IDA | ||
| cytoplasm | C | IEA | IEA | |
| plasma membrane | C | ISS | ||
| lipoprotein binding | F | TAS | ISS | |
| calcium ion binding | F | TAS IEA | RCA | ISS ISS |
| lipid transporter activity | F | TAS | ISS | |
| metal ion binding | F | IEA | ||
| receptor activity | F | TAS | IEA | ISS ISS |
| protein binding | F | IPI | IPI IMP | |
| protein kinase C activation | P | IMP | ||
| negative regulation of Wnt receptor signaling pathway | P | IEA | IDA | ISS |
| positive regulation of anti-apoptosis | P | IMP | ||
| endocytosis | P | IEA | IEA | ISS |
| cell proliferation | P | TAS | ISS IMP | |
| lipoprotein metabolic process | P | IEP | ||
| multicellular organismal development | P | IEA | IEA | |
| aging | P | IEP | ||
| lipid metabolic process | P | TAS | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| homeostasis/metabolism phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Myocardial Infarction | D | ISS | ||
| Arteriosclerosis | D | ISS | ||
| Retinal Neovascularization | D | IEP | ||
| Prostatic Intraepithelial Neoplasia | D | IEP | ||
| Coronary Disease | D | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Alzheimer's disease (05010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |