IPI report for IPI00398992

IpiRecord: IPI00398992

IPI00398992 - CHD8, ISOFORM 1 OF CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 8.
Uniprot Accession: Q6ZNL7
Uniprot ID: Q6ZNL7_HUMAN
Mapping: Chr 14, 20923485 - 20975242
Entrez Gene: 57680
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: Q9HCK8-1 UniProtKB/Swiss-Prot: CHD8_HUMAN Vega: OTTHUMP00000066251 REFSEQ_VALIDATED: NP_065971 REFSEQ_VALIDATED: GI:114326455 UniProtKB/TrEMBL: Q4G0D8 UniProtKB/TrEMBL: Q4G0D8_HUMAN UniProtKB/TrEMBL: Q6DKH9 UniProtKB/TrEMBL: Q6DKH9_HUMAN UniProtKB/TrEMBL: Q6P440 UniProtKB/TrEMBL: Q6P440_HUMAN UniProtKB/TrEMBL: Q6ZNL7 UniProtKB/TrEMBL: Q6ZNL7_HUMAN ENSEMBL: ENSP00000262707 ENSEMBL: ENSG00000100888 H-InvDB: HIT000306354 UniParc: UPI000066880F HGNC: 20153 Entrez Gene: 57680 UniGene: Hs.530698 RZPD: Hs.530698 InterPro: IPR006576 InterPro: IPR000953 InterPro: IPR014001 InterPro: IPR001650 InterPro: IPR014021 InterPro: IPR000330 Pfam: PF00385 Pfam: PF00271 Pfam: PF00176 Pfam: PF07533 SMART: SM00592 SMART: SM00298 SMART: SM00487 SMART: SM00490 PROSITE: PS50013 PROSITE: PS51192 PROSITE: PS51194

IPI00398992 - CHD8, ISOFORM 1 OF CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 8.

Uniprot Accession: Q6ZNL7

Uniprot ID: Q6ZNL7_HUMAN

Mapping: Chr 14, 20923485 - 20975242

Entrez Gene: 57680

Entrez MapView: Geneprod

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12199)
Rat: Chd8, SIMILAR TO CHROMODOMAIN HELICASE DNA BINDING PROTEIN 8.
Mouse: Chd8, CHD8 PROTEIN.
Mouse: Chd8, PROTEIN.
Mouse: Chd8, CHROMODOMAIN HELICASE DNA BINDING PROTEIN 8.
Human: CHD8, ISOFORM 1 OF CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 8.
Human: CHD8, ISOFORM 2 OF CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 8.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12199)

Rat: Chd8, SIMILAR TO CHROMODOMAIN HELICASE DNA BINDING PROTEIN 8.

Mouse: Chd8, CHD8 PROTEIN.

Mouse: Chd8, PROTEIN.

Mouse: Chd8, CHROMODOMAIN HELICASE DNA BINDING PROTEIN 8.

Human: CHD8, ISOFORM 1 OF CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 8.

Human: CHD8, ISOFORM 2 OF CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 8.

Annotations for CHD8 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Mouse	Rat
cellular_component	C	ND
chromatin	C		IEA
nucleus	C	IEA	ISS IEA
chromatin binding	F		IEA
helicase activity	F	IEA
beta-catenin binding	F		IPI
transcription regulator activity	F		ISS
protein binding	F	IPI
molecular_function	F	ND
regulation of transcription, DNA-dependent	P		ISS
in utero embryonic development	P	IMP
negative regulation of Wnt receptor signaling pathway	P		IDA
chromatin assembly or disassembly	P		IEA

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
embryogenesis phenotype	MP		Un
lethality-embryonic/perinatal	MP		Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Wnt signaling pathway (04310)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway