IPI report for IPI00418163

IpiRecord: IPI00418163

IPI00418163 - C4B, COMPLEMENT COMPONENT 4B PREPROPROTEIN.
Uniprot Accession: Q9UNU2
Uniprot ID: Q9UNU2_HUMAN
Mapping: Chr 6, 32084607 - 32098878
Entrez Gene: 721
Entrez MapView:
+All IPI Database Cross References Vega: OTTHUMP00000029269 Vega: OTTHUMP00000029709 REFSEQ_REVIEWED: NP_001002029 REFSEQ_REVIEWED: GI:50345296 UniProtKB/TrEMBL: Q30211 UniProtKB/TrEMBL: Q30211_HUMAN UniProtKB/TrEMBL: Q6U2E9 UniProtKB/TrEMBL: Q6U2E9_HUMAN UniProtKB/TrEMBL: Q6U2F8 UniProtKB/TrEMBL: Q6U2F8_HUMAN UniProtKB/TrEMBL: Q6U2G0 UniProtKB/TrEMBL: Q6U2G0_HUMAN UniProtKB/TrEMBL: Q6U2G1 UniProtKB/TrEMBL: Q6U2G1_HUMAN UniProtKB/TrEMBL: Q6U2H4 UniProtKB/TrEMBL: Q6U2H4_HUMAN UniProtKB/TrEMBL: Q6U2L1 UniProtKB/TrEMBL: Q6U2L1_HUMAN UniProtKB/TrEMBL: Q6U2L6 UniProtKB/TrEMBL: Q6U2L6_HUMAN UniProtKB/TrEMBL: Q6U2L7 UniProtKB/TrEMBL: Q6U2L7_HUMAN UniProtKB/TrEMBL: Q6U2M2 UniProtKB/TrEMBL: Q6U2M2_HUMAN UniProtKB/TrEMBL: Q6U2M5 UniProtKB/TrEMBL: Q6U2M5_HUMAN UniProtKB/TrEMBL: Q6VCV8 UniProtKB/TrEMBL: Q6VCV8_HUMAN UniProtKB/TrEMBL: Q96SA7 UniProtKB/TrEMBL: Q96SA7_HUMAN UniProtKB/TrEMBL: Q96SA8 UniProtKB/TrEMBL: Q96SA8_HUMAN UniProtKB/TrEMBL: Q9UNU2 UniProtKB/TrEMBL: Q9UNU2_HUMAN ENSEMBL: ENSP00000364444 ENSEMBL: ENSG00000204342 ENSEMBL: ENSP00000372648 ENSEMBL: ENSG00000206264 UniParc: UPI000016A806 HGNC: 1323 HGNC: 1324 Entrez Gene: 720 Entrez Gene: 721 UniGene: Hs.534847 UniGene: Hs.655564 CCDS: CCDS4734.1 RZPD: Hs.534847 InterPro: IPR009048 InterPro: IPR011626 InterPro: IPR002890 InterPro: IPR011625 InterPro: IPR000020 InterPro: IPR001840 InterPro: IPR001599 InterPro: IPR001134 InterPro: IPR008930 Pfam: PF00207 Pfam: PF07678 Pfam: PF01835 Pfam: PF07703 Pfam: PF07677 Pfam: PF01821 Pfam: PF01759 PRINTS: PR00004 ProDom: PD003264 SMART: SM00104 SMART: SM00643 PROSITE: PS00477 PROSITE: PS01177 PROSITE: PS01178 PROSITE: PS50189 SUPERFAMILY: SSF49410 SUPERFAMILY: SSF47686 SUPERFAMILY: SSF48239 GENE3D: G3DSA:1.20.91.20 GENE3D: G3DSA:2.60.40.690

IPI00418163 - C4B, COMPLEMENT COMPONENT 4B PREPROPROTEIN.

Uniprot Accession: Q9UNU2

Uniprot ID: Q9UNU2_HUMAN

Mapping: Chr 6, 32084607 - 32098878

Entrez Gene: 721

Entrez MapView: Geneprod

+All IPI Database Cross References

Vega: OTTHUMP00000029269
Vega: OTTHUMP00000029709
REFSEQ_REVIEWED: NP_001002029
REFSEQ_REVIEWED: GI:50345296
UniProtKB/TrEMBL: Q30211
UniProtKB/TrEMBL: Q30211_HUMAN
UniProtKB/TrEMBL: Q6U2E9
UniProtKB/TrEMBL: Q6U2E9_HUMAN
UniProtKB/TrEMBL: Q6U2F8
UniProtKB/TrEMBL: Q6U2F8_HUMAN
UniProtKB/TrEMBL: Q6U2G0
UniProtKB/TrEMBL: Q6U2G0_HUMAN
UniProtKB/TrEMBL: Q6U2G1
UniProtKB/TrEMBL: Q6U2G1_HUMAN
UniProtKB/TrEMBL: Q6U2H4
UniProtKB/TrEMBL: Q6U2H4_HUMAN
UniProtKB/TrEMBL: Q6U2L1
UniProtKB/TrEMBL: Q6U2L1_HUMAN
UniProtKB/TrEMBL: Q6U2L6
UniProtKB/TrEMBL: Q6U2L6_HUMAN
UniProtKB/TrEMBL: Q6U2L7
UniProtKB/TrEMBL: Q6U2L7_HUMAN
UniProtKB/TrEMBL: Q6U2M2
UniProtKB/TrEMBL: Q6U2M2_HUMAN
UniProtKB/TrEMBL: Q6U2M5
UniProtKB/TrEMBL: Q6U2M5_HUMAN
UniProtKB/TrEMBL: Q6VCV8
UniProtKB/TrEMBL: Q6VCV8_HUMAN
UniProtKB/TrEMBL: Q96SA7
UniProtKB/TrEMBL: Q96SA7_HUMAN
UniProtKB/TrEMBL: Q96SA8
UniProtKB/TrEMBL: Q96SA8_HUMAN
UniProtKB/TrEMBL: Q9UNU2
UniProtKB/TrEMBL: Q9UNU2_HUMAN
ENSEMBL: ENSP00000364444
ENSEMBL: ENSG00000204342
ENSEMBL: ENSP00000372648
ENSEMBL: ENSG00000206264
UniParc: UPI000016A806
HGNC: 1323
HGNC: 1324
Entrez Gene: 720
Entrez Gene: 721
UniGene: Hs.534847
UniGene: Hs.655564
CCDS: CCDS4734.1
RZPD: Hs.534847
InterPro: IPR009048
InterPro: IPR011626
InterPro: IPR002890
InterPro: IPR011625
InterPro: IPR000020
InterPro: IPR001840
InterPro: IPR001599
InterPro: IPR001134
InterPro: IPR008930
Pfam: PF00207
Pfam: PF07678
Pfam: PF01835
Pfam: PF07703
Pfam: PF07677
Pfam: PF01821
Pfam: PF01759
PRINTS: PR00004
ProDom: PD003264
SMART: SM00104
SMART: SM00643
PROSITE: PS00477
PROSITE: PS01177
PROSITE: PS01178
PROSITE: PS50189
SUPERFAMILY: SSF49410
SUPERFAMILY: SSF47686
SUPERFAMILY: SSF48239
GENE3D: G3DSA:1.20.91.20
GENE3D: G3DSA:2.60.40.690

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_17788)
Rat: C4a, COMPLEMENT C4 PRECURSOR.
Human: C4B, COMPLEMENT COMPONENT 4B PREPROPROTEIN.
Human: C4B, COMPLEMENT C4-B PRECURSOR.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_17788)

Rat: C4a, COMPLEMENT C4 PRECURSOR.

Human: C4B, COMPLEMENT COMPONENT 4B PREPROPROTEIN.

Human: C4B, COMPLEMENT C4-B PRECURSOR.

Annotations for C4B and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Rat
extracellular region	C	IEA	IDA
molecular_function	F		ND
protein binding	F	IEA
endopeptidase inhibitor activity	F	IEA	IEA
complement activation, classical pathway	P	IEA	NAS
inflammatory response	P	IEA	NAS
complement activation	P	IEA	TAS ISS
innate immune response	P	IEA	IEA
positive regulation of smooth muscle contraction	P		NAS
immunoglobulin mediated immune response	P		ISS

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
classical complement pathway	W			IMP

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Complement and coagulation cascades (04610)	Present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway