| IPI00419916 - ALPL, ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME PRECURSOR. | |
|---|---|
| Uniprot Accession: Q9UIL5 | |
| Uniprot ID: Q9UIL5_HUMAN | |
| Mapping: Chr 1, 21708452 - 21777492 | |
| Entrez Gene: 249 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5623) |
|---|
| Rat: Alpl, ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME PRECURSOR. |
| Mouse: Akp2, ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME PRECURSOR. |
| Mouse: Akp2, ALKALINE PHOSPHATASE 2, LIVER. |
| Mouse: Akp2, ALKALINE PHOSPHATASE. |
| Human: ALPL, ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME PRECURSOR. |
| Human: ALPL, ALKALINE PHOSPHATASE, LIVER/BONE/KIDNEY. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| extracellular space | C | RCA | ISS | |
| cellular_component | C | ND | ||
| membrane | C | IEA | IEA | IEA |
| integral to membrane | C | IEA | ||
| plasma membrane | C | IDA | ||
| GPI anchor binding | F | IEA | IEA | IEA |
| zinc ion binding | F | IEA | IEA | IEA |
| alkaline phosphatase activity | F | IEA | IDA | TAS IDA IEA |
| magnesium ion binding | F | IEA | IEA | IEA |
| metal ion binding | F | IEA | ||
| hydrolase activity | F | IEA | IEA | IEA |
| ossification | P | IEA | ||
| response to glucocorticoid stimulus | P | IDA | ||
| metabolic process | P | IEA | IEA | IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| craniofacial phenotype | MP | Un | ||
| adipose tissue phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| behavior/neurological phenotype | MP | Un Un | ||
| endocrine/exocrine gland phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| skeleton phenotype | MP | Un | ||
| lethality-postnatal | MP | Un Un | ||
| muscle phenotype | MP | Un | ||
| nervous system phenotype | MP | Un Un | ||
| respiratory system phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| hematopoietic system phenotype | MP | Un | ||
| reproductive system phenotype | MP | Un | ||
| growth/size phenotype | MP | Un Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Hypophosphatasia | D | ISS | ||
| Hypercholesterolemia | D | IEP | ||
| Metabolic Syndrome X | D | ISS | ||
| Fatty Liver | D | ISS | ||
| Arteriosclerosis | D | ISS | ||
| Hyperlipidemia, Familial Combined | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| glycerolipid metabolic pathway | W | IEA | ||
| gamma-hexachlorocyclohexane degradation pathway | W | IEA | ||
| pathway of folate cycle/metabolism | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Folate biosynthesis (00790) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| gamma-Hexachlorocyclohexane degradation (00361) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |