IpiRecord: IPI00419916

IPI00419916 - ALPL, ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME PRECURSOR.
Uniprot Accession: Q9UIL5
Uniprot ID: Q9UIL5_HUMAN
Mapping: Chr 1, 21708452 - 21777492
Entrez Gene: 249
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5623)
Rat: Alpl, ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME PRECURSOR.
Mouse: Akp2, ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME PRECURSOR.
Mouse: Akp2, ALKALINE PHOSPHATASE 2, LIVER.
Mouse: Akp2, ALKALINE PHOSPHATASE.
Human: ALPL, ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME PRECURSOR.
Human: ALPL, ALKALINE PHOSPHATASE, LIVER/BONE/KIDNEY.

Annotations for ALPL and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCRCA ISS 
cellular_componentCND 
membraneCIEA IEA IEA 
integral to membraneCIEA 
plasma membraneCIDA 
GPI anchor bindingFIEA IEA IEA 
zinc ion bindingFIEA IEA IEA 
alkaline phosphatase activityFIEA IDA TAS IDA IEA 
magnesium ion bindingFIEA IEA IEA 
metal ion bindingFIEA 
hydrolase activityFIEA IEA IEA 
ossificationPIEA 
response to glucocorticoid stimulusPIDA 
metabolic processPIEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (15)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
craniofacial phenotypeMPUn
adipose tissue phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
behavior/neurological phenotypeMPUn Un
endocrine/exocrine gland phenotypeMPUn
immune system phenotypeMPUn
skeleton phenotypeMPUn
lethality-postnatalMPUn Un
muscle phenotypeMPUn
nervous system phenotypeMPUn Un
respiratory system phenotypeMPUn
digestive/alimentary phenotypeMPUn
hematopoietic system phenotypeMPUn
reproductive system phenotypeMPUn
growth/size phenotypeMPUn Un

Disease (6)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
HypophosphatasiaDISS
HypercholesterolemiaDIEP
Metabolic Syndrome XDISS
Fatty LiverDISS
ArteriosclerosisDISS
Hyperlipidemia, Familial CombinedDISS

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
glycerolipid metabolic pathwayWIEA
gamma-hexachlorocyclohexane degradation pathwayWIEA
pathway of folate cycle/metabolismWIEA

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Folate biosynthesis (00790)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
gamma-Hexachlorocyclohexane degradation (00361)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway