IPI report for IPI00479186

IpiRecord: IPI00479186

IPI00479186 - PKM2, ISOFORM M2 OF PYRUVATE KINASE ISOZYMES M1/M2.
Uniprot Accession: P14618-1
Uniprot ID: KPYM_HUMAN
Mapping: Chr 15, 70278424 - 70310738
Entrez Gene: 5315
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: P14618-1 UniProtKB/Swiss-Prot: KPYM_HUMAN Vega: OTTHUMP00000043775 Vega: OTTHUMP00000176444 REFSEQ_REVIEWED: NP_002645 REFSEQ_REVIEWED: GI:33286418 ENSEMBL: ENSP00000373740 ENSEMBL: ENSG00000067225 ENSEMBL: ENSP00000373741 ENSEMBL: ENSG00000067225 ENSEMBL: ENSP00000373744 ENSEMBL: ENSG00000067225 H-InvDB: HIT000029665 UniParc: UPI0000169DBC HGNC: 9021 Entrez Gene: 5315 UniGene: Hs.534770 CCDS: CCDS32284.1 UTRdb: BB234778 UTRdb: BB275025 UTRdb: BB284336 UTRdb: BB398366 UTRdb: BB398985 UTRdb: CC446511 RZPD: Hs.534770 InterPro: IPR001697 InterPro: IPR015813 InterPro: IPR015794 InterPro: IPR011037 InterPro: IPR015793 InterPro: IPR015795 Pfam: PF00224 Pfam: PF02887 ProDom: PD001009 TIGRFAMs: TIGR01064 PROSITE: PS00110 SUPERFAMILY: SSF50800 SUPERFAMILY: SSF52935 PANTHER: PTHR11817 GENE3D: G3DSA:3.20.20.60 GENE3D: G3DSA:3.40.1380.20

IPI00479186 - PKM2, ISOFORM M2 OF PYRUVATE KINASE ISOZYMES M1/M2.

Uniprot Accession: P14618-1

Uniprot ID: KPYM_HUMAN

Mapping: Chr 15, 70278424 - 70310738

Entrez Gene: 5315

Entrez MapView: Geneprod

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_8097)
Rat: Pkm2, ISOFORM M1 OF PYRUVATE KINASE ISOZYMES M1/M2.
Mouse: Pkm2, ISOFORM M2 OF PYRUVATE KINASE ISOZYMES M1/M2.
Mouse: Pkm2, ISOFORM M1 OF PYRUVATE KINASE ISOZYMES M1/M2.
Rat: Pkm2, ISOFORM M2 OF PYRUVATE KINASE ISOZYMES M1/M2.
Human: PKM2, ISOFORM M1 OF PYRUVATE KINASE ISOZYMES M1/M2.
Human: PKM2, ISOFORM M2 OF PYRUVATE KINASE ISOZYMES M1/M2.
Human: PKM2, PYRUVATE KINASE.
Human: PKM2, 30 KDA PROTEIN.
Human: PKM2, PYRUVATE KINASE.
Human: PKM2, 58 KDA PROTEIN.
Human: PKM2, 26 KDA PROTEIN.
Human: PKM2, 23 KDA PROTEIN.
Human: PKM2, 24 KDA PROTEIN.
Human: PKM2, 19 KDA PROTEIN.
Human: PKM2, 10 KDA PROTEIN.
Human: PKM2, PYRUVATE KINASE (FRAGMENT).

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_8097)

Rat: Pkm2, ISOFORM M1 OF PYRUVATE KINASE ISOZYMES M1/M2.

Mouse: Pkm2, ISOFORM M2 OF PYRUVATE KINASE ISOZYMES M1/M2.

Mouse: Pkm2, ISOFORM M1 OF PYRUVATE KINASE ISOZYMES M1/M2.

Rat: Pkm2, ISOFORM M2 OF PYRUVATE KINASE ISOZYMES M1/M2.

Human: PKM2, ISOFORM M1 OF PYRUVATE KINASE ISOZYMES M1/M2.

Human: PKM2, ISOFORM M2 OF PYRUVATE KINASE ISOZYMES M1/M2.

Human: PKM2, PYRUVATE KINASE.

Human: PKM2, 30 KDA PROTEIN.

Human: PKM2, PYRUVATE KINASE.

Human: PKM2, 58 KDA PROTEIN.

Human: PKM2, 26 KDA PROTEIN.

Human: PKM2, 23 KDA PROTEIN.

Human: PKM2, 24 KDA PROTEIN.

Human: PKM2, 19 KDA PROTEIN.

Human: PKM2, 10 KDA PROTEIN.

Human: PKM2, PYRUVATE KINASE (FRAGMENT).

Annotations for PKM2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
cytosol	C			ISS
mitochondrion	C		IDA	ISS
transferase activity	F	IEA	IEA
protein binding	F			ISS
pyruvate kinase activity	F	IEA	IDA IDA	ISS ISS
potassium ion binding	F	IEA
catalytic activity	F	IEA	IEA
kinase activity	F		IEA
magnesium ion binding	F	IEA	IEA
metal ion binding	F		IEA
glycolysis	P	IEA	IEA	ISS

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (4)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Rat
glycolysis/gluconeogenesis pathway	W	IEA
pyruvate metabolic pathway	W	IEA
purine metabolic pathway	W	IEA
carbon fixation pathway	W	IEA

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Purine metabolism (00230)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Glycolysis / Gluconeogenesis (00010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Type II diabetes mellitus (04930)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Carbon fixation (00710)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Pyruvate metabolism (00620)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Insulin signaling pathway (04910)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway