IpiRecord: IPI00514067

IPI00514067 - GNAQ, GUANINE NUCLEOTIDE BINDING PROTEIN (G PROTEIN), Q POLYPEPTIDE.
Uniprot Accession: Q5T8F3
Uniprot ID: Q5T8F3_HUMAN
Mapping: Chr 9, 79520823 - 79836194
Entrez Gene: 2776
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1565)
Rat: Gnaq, GUANINE NUCLEOTIDE BINDING PROTEIN, ALPHA Q POLYPEPTIDE.
Mouse: Gnaq, INSERT SEQUENCE.
Human: GNAQ, GUANINE NUCLEOTIDE BINDING PROTEIN.
Human: GNAQ, GUANINE NUCLEOTIDE BINDING PROTEIN (G PROTEIN), Q POLYPEPTIDE.

Annotations for GNAQ and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
caveolar membraneCIDA 
plasma membraneCTAS TAS ISS 
cytoplasmCTAS ISS 
heterotrimeric G-protein complexCNR TAS TAS TAS ISS ISS 
caveolaCIDA 
guanyl nucleotide bindingFIEA IEA 
nucleotide bindingFIEA IEA IEA 
GTPase activityFTAS TAS TAS ISS ISS TAS 
signal transducer activityFIEA IEA IEA IEA 
GTP bindingFIEA IEA IEA IEA IEA 
G-protein coupled receptor protein signaling pathwayPIEA IMP ISS IEA 
anti-apoptosisPIMP 
signal transductionPIEA IEA IEA IEA 
heart developmentPIEA IMP ISS IEA 
positive regulation of apoptosisPTAS 
embryonic digit morphogenesisPIEA IGI ISS IEA 
phospholipase C activationPTAS ISS IMP 
regulation of melanocyte differentiationPIEA IMP ISS IEA 
protein amino acid ADP-ribosylationPIEA RCA ISS IEA 
neuron remodelingPIEA IMP ISS IEA 
G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)PIMP 
regulation of action potentialPIEA IMP ISS IEA 
G-protein signaling, adenylate cyclase activating pathwayPIEA IDA ISS IEA 
positive regulation of smooth muscle cell proliferationPIMP 
negative regulation of potassium ion transportPIMP 
skeletal developmentPIEA IMP ISS IEA 
blood coagulationPTAS ISS 
glutamate signaling pathwayPIEA IMP ISS IEA 
dopamine receptor, phospholipase C activating pathwayPIGI 
pigmentation during developmentPIEA IMP ISS IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (22)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
craniofacial phenotypeMPUn Un
pigmentation phenotypeMPUn
behavior/neurological phenotypeMPUn Un
homeostasis/metabolism phenotypeMPUn Un
lethality-embryonic/perinatalMPUn Un
skeleton phenotypeMPUn
muscle phenotypeMPUn
life span-post-weaning/agingMPUn
nervous system phenotypeMPUn
growth/size phenotypeMPUn
hematopoietic system phenotypeMPUn Un
respiratory system phenotypeMPUn
cardiovascular system phenotypeMPUn Un
normal phenotypeMPUn
limbs/digits/tail phenotypeMPUn
hearing/vestibular/ear phenotypeMPUn Un
touch/vibrissae phenotypeMPUn
abnormal cardiovascular system morphologyNISS
embryonic lethalityNISS
abnormal craniofacial morphologyNISS
perinatal lethalityNISS

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
CardiomegalyDISS
Cardiomyopathy, CongestiveDISS

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
G protein signaling pathway via Galphaq familyWIMP
orexin/hypocretin signaling pathway through the orexin/hypocretin receptor 1WIMP
orexin/hypocretin signaling pathway through the orexin/hypocretin receptor 2WIMP

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
GnRH signaling pathway (04912)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term depression (04730)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Calcium signaling pathway (04020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term potentiation (04720)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway