IpiRecord: IPI00514407

IPI00514407 - HMGCL, 19 KDA PROTEIN.
Uniprot Accession: -NA-
Uniprot ID: -NA-
Mapping: Chr 1, 24000909 - 24025264
Entrez Gene: 3155
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5741)
Rat: Hmgcl, HYDROXYMETHYLGLUTARYL-COA LYASE, MITOCHONDRIAL PRECURSOR.
Mouse: Hmgcl, HYDROXYMETHYLGLUTARYL-COA LYASE, MITOCHONDRIAL PRECURSOR.
Mouse: Hmgcl, FULL INSERT SEQUENCE.
Human: HMGCL, HYDROXYMETHYLGLUTARYL-COA LYASE, MITOCHONDRIAL PRECURSOR.
Human: HMGCL, 19 KDA PROTEIN.
Human: HMGCL, UNCHARACTERIZED PROTEIN HMGCL.

Annotations for HMGCL and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
mitochondrial inner membraneCIDA ISS IEA 
mitochondrial matrixCNAS ISS 
extracellular spaceCRCA ISS 
mitochondrionCIEA IDA ISS IDA IDA IEA 
hydroxymethylglutaryl-CoA lyase activityFIEA IEA IEA ISS IDA IEA 
lyase activityFIEA IEA IEA 
carboxylic acid bindingFIPI 
catalytic activityFIEA IEA 
acyl-CoA bindingFIPI 
generation of precursor metabolites and energyPNR ISS 
metabolic processPIEA IEA IEA 
amino acid metabolic processPNR ISS 
acyl-CoA metabolic processPIDA 
ketone body biosynthetic processPIDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (5)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn
cardiovascular system phenotypeMPUn
growth/size phenotypeMPUn
liver/biliary system phenotypeMPUn

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Amino Acid Metabolism, Inborn ErrorsDISS

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
valine, leucine and isoleucine degradation pathwayWIEA
ketone bodies metabolic pathwayWIEA
butanoate metabolic pathwayWIEA

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Synthesis and degradation of ketone bodies (00072)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Valine, leucine and isoleucine degradation (00280)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Butanoate metabolism (00650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway