| IPI00514444 - IDE, INSULIN-DEGRADING ENZYME. | |
|---|---|
| Uniprot Accession: Q5T5N3 | |
| Uniprot ID: Q5T5N3_HUMAN | |
| Mapping: Chr 10, 94201421 - 94323813 | |
| Entrez Gene: 3416 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1839) |
|---|
| Rat: Ide, INSULIN-DEGRADING ENZYME. |
| Mouse: Ide, INSULIN-DEGRADING ENZYME. |
| Mouse: Ide, SEQUENCE (FRAGMENT). |
| Mouse: Ide, INSULIN DEGRADING ENZYME. |
| Human: IDE, INSULIN-DEGRADING ENZYME. |
| Human: IDE, INSULIN-DEGRADING ENZYME. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytoplasm | C | IEA | IEA | |
| peroxisome | C | TAS | ISS ISS | |
| extracellular space | C | TAS | RCA | ISS ISS |
| soluble fraction | C | TAS | ISS | |
| hydrolase activity | F | IEA | ||
| signal transducer activity | F | TAS TAS | ISS | |
| insulysin activity | F | TAS | IEA | TAS ISS IEA |
| metallopeptidase activity | F | IEA | ||
| peptidase activity | F | IEA | TAS | |
| metal ion binding | F | IEA | IEA | IEA |
| catalytic activity | F | IEA | ||
| metalloendopeptidase activity | F | IEA | IEA | |
| zinc ion binding | F | IEA | IEA IEA | IEA |
| sex differentiation | P | TAS | ISS | |
| cell-cell signaling | P | NR | ISS | |
| peptide catabolic process | P | TAS | ||
| signal transduction | P | NAS | ISS | |
| proteolysis | P | TAS IEA | IEA | ISS IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| homeostasis/metabolism phenotype | MP | Un | ||
| other phenotype | MP | Un | ||
| normal phenotype | MP | Un | ||
| nervous system phenotype | MP | Un | ||
| amyloidosis | N | ISS |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Diabetes Mellitus, Non-Insulin-Dependent | D | ISSISS | ||
| Alzheimer Disease | D | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Alzheimer's disease (05010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |