| IPI00514814 - AKR1C1, ALDO-KETO REDUCTASE FAMILY 1, MEMBER C1. | |
|---|---|
| Uniprot Accession: Q5SR14 | |
| Uniprot ID: Q5SR14_HUMAN | |
| Mapping: Chr 10, 4995445 - 5012159 | |
| Entrez Gene: 1645 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13345) |
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| Rat: Akr1c6, ALDO-KETO REDUCTASE FAMILY 1, MEMBER C6. |
| Mouse: Akr1c6, ESTRADIOL 17 BETA-DEHYDROGENASE 5. |
| Human: AKR1C1, ALDO-KETO REDUCTASE FAMILY 1 MEMBER C1. |
| Human: AKR1C1, ALDO-KETO REDUCTASE FAMILY 1, MEMBER C1. |
| Human: AKR1C1, UNCHARACTERIZED PROTEIN AKR1C1. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytoplasm | C | IEA | ||
| cellular_component | C | ND | ||
| cytosol | C | IDA | ISS | |
| 20-alpha-hydroxysteroid dehydrogenase activity | F | IEA | ||
| aldo-keto reductase activity | F | TAS | ISS | |
| trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity | F | IDA | ISS | |
| bile acid binding | F | IDA | ||
| 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity | F | IDA | ISS | |
| carboxylic acid binding | F | ISS | ||
| oxidoreductase activity | F | IEA | RCA | ISS IEA |
| estradiol 17-beta-dehydrogenase activity | F | IDA | ISS IEA | |
| digestion | P | IDA | ISS | |
| lipid biosynthetic process | P | IEA | ||
| bile acid metabolic process | P | IDA | ISS | |
| cholesterol homeostasis | P | TAS | ISS | |
| steroid metabolic process | P | IDA | ISS | |
| steroid biosynthetic process | P | RCA | ISS | |
| protein homooligomerization | P | IDA | ISS | |
| xenobiotic metabolic process | P | NAS | ISS | |
| bile acid and bile salt transport | P | TAS | ISS | |
| cholesterol absorption | P | TAS | ISS | |
| electron transport | P | IDA | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Obesity | D | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Metabolism of xenobiotics by cytochrome P450 (00980) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Glycine, serine and threonine metabolism (00260) | Not present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Fructose and mannose metabolism (00051) | Not present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Bisphenol A degradation (00363) | Not present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Lysine degradation (00310) | Not present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Galactose metabolism (00052) | Not present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Tetrachloroethene degradation (00625) | Not present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Linoleic acid metabolism (00591) | Not present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Bile acid biosynthesis (00120) | Not present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Butanoate metabolism (00650) | Not present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |