IpiRecord: IPI00549340

IPI00549340 - NRP1, NEUROPILIN 1.
Uniprot Accession: Q9H2D7
Uniprot ID: Q9H2D7_HUMAN
Mapping: Chr 10, 33506426 - 33665196
Entrez Gene: 8829
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14103)
Rat: Nrp1, NEUROPILIN-1 PRECURSOR.
Mouse: Nrp1, NEUROPILIN-1 PRECURSOR.
Human: NRP1, MUSCLE TYPE NEUROPILIN 1.
Human: NRP1, ISOFORM 1 OF NEUROPILIN-1 PRECURSOR.
Human: NRP1, NEUROPILIN 1.
Human: NRP1, NEUROPILIN 1.
Human: NRP1, NEUROPILIN 1.
Human: NRP1, ISOFORM 2 OF NEUROPILIN-1 PRECURSOR.
Human: NRP1, NEUROPILIN 1.
Human: NRP1, NEUROPILIN 1.
Human: NRP1, NEUROPILIN 1.
Human: NRP1, NEUROPILIN 1.
Human: NRP1, NEUROPILIN 1.
Human: NRP1, NEUROPILIN 1.

Annotations for NRP1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCIC ISS 
endoplasmic reticulumCIDA 
membrane fractionCISS 
membraneCIEA IEA IEA IEA 
integral to membraneCRCA NAS ISS IEA 
protein bindingFIPI IPI ISS IEA 
receptor activityFIEA IEA 
semaphorin receptor activityFIGI IPI IPI TAS ISS IEA 
vascular endothelial growth factor receptor activityFIPI IMP ISS 
axon guidancePIMP IMP IMP ISS ISS IEA 
cell differentiationPIEA IEA 
dendrite developmentPIMP ISS IEA 
cell-cell signalingPISS 
axonal fasciculationPIMP 
negative regulation of axon extensionPIGI ISS IEA 
nervous system developmentPIEA NAS IEA 
heart developmentPIGI ISS IEA 
cell adhesionPIEA IEA IEA 
positive regulation of cell proliferationPISS 
signal transductionPISS 
angiogenesisPIMP IMP ISS IEA 
vascular endothelial growth factor receptor signaling pathwayPIMP IMP ISS IEA 
cell migrationPIMP ISS 
patterning of blood vesselsPIMP 
multicellular organismal developmentPIEA IEA 
organ morphogenesisPISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
craniofacial phenotypeMPUn
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn Un
lethality-postnatalMPUn
nervous system phenotypeMPUn Un
cardiovascular system phenotypeMPUn Un
growth/size phenotypeMPUn Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
vascular endothelial growth factor signaling pathwayWIMPISS

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Axon guidance (04360)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway