IpiRecord: IPI00554805

IPI00554805 - CD80, COSTIMULATORY FACTOR CD80 TYPE 2.
Uniprot Accession: Q5DTA9
Uniprot ID: Q5DTA9_HUMAN
Mapping: Chr 3, 120725835 - 120761139
Entrez Gene: 941
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10497)
Rat: Cd80, B7.1.
Mouse: Cd80, ISOFORM 2 OF T-LYMPHOCYTE ACTIVATION ANTIGEN CD80 PRECURSOR.
Mouse: Cd80, LIBRARY, CLONE:F630021B16 PRODUCT:CD80 ANTIGEN, FULL INSERT SEQUENCE.
Mouse: Cd80, B LYMPHOCYTE ACTIVATION ANTIGEN B7-1 (FRAGMENT).
Human: CD80, T-LYMPHOCYTE ACTIVATION ANTIGEN CD80 PRECURSOR.
Human: CD80, COSTIMULATORY FACTOR CD80 TYPE 1.
Human: CD80, COSTIMULATORY FACTOR CD80 TYPE 2.

Annotations for CD80 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCNAS IEA ISS 
extracellular spaceCRCA ISS 
integral to membraneCIC IEA RCA ISS ISS 
membraneCIEA IEA 
external side of plasma membraneCIDA IDA ISS 
transcription activator activityFNAS ISS 
receptor activityFIEA 
receptor bindingFNR ISS 
coreceptor activityFNAS ISS 
positive regulation of peptidyl-tyrosine phosphorylationPIDA ISS 
T cell costimulationPIDA 
positive regulation of signal transductionPNAS ISS 
intracellular signaling cascadePNAS ISS 
cell-cell signalingPIC ISS 
positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic processPNAS ISS 
activated T cell proliferationPISS 
immune responsePNR ISS 
T cell activationPIC ISS ISS 
positive regulation of T-helper 1 cell differentiationPNAS ISS 
positive regulation of interleukin-2 biosynthetic processPNAS ISS 
positive regulation of transcriptionPNAS ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (6)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
immune system phenotypeMPUn Un
nervous system phenotypeMPUn
digestive/alimentary phenotypeMPUn
hematopoietic system phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Cell adhesion molecules (CAMs) (04514)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Type I diabetes mellitus (04940)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway