IpiRecord: IPI00555908

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
proteinaceous extracellular matrix	C			ISS
basement membrane	C			IDA
membrane	C	IEA	IEA IEA	IEA
cytoplasm	C		IDA	ISS
extracellular space	C		RCA IDA IDA	ISS ISS IDA
protein homodimerization activity	F			ISS IDA
growth factor activity	F	IEA	IEA IEA	IDA ISS IEA
heparin binding	F		IEA	ISS
vascular endothelial growth factor receptor binding	F			TAS ISS
extracellular matrix binding	F			ISS
cell maturation	P		IMP
camera-type eye morphogenesis	P		IMP
negative regulation of bone resorption	P			IMP
positive regulation of vascular permeability	P			IMP
negative regulation of apoptosis	P			ISS
nervous system development	P			IDA ISS
positive regulation of endothelial cell proliferation	P		IDA
ovarian follicle development	P		IMP
positive regulation of epithelial cell proliferation	P		IMP	ISS
positive regulation of mesenchymal cell proliferation	P		IDA
T-helper 1 type immune response	P			IDA
positive regulation of vascular endothelial growth factor receptor signaling pathway	P			ISS
blood vessel development	P		IMP IMP	ISS
response to hypoxia	P			ISS IDA
induction of positive chemotaxis	P			ISS
surfactant homeostasis	P		IMP
epithelial cell differentiation	P		IMP	ISS
regulation of progression through cell cycle	P	IEA	IEA	IEA
branching morphogenesis of a tube	P		IDA
positive regulation of signal transduction	P			IDA
positive regulation of cell proliferation	P			TAS ISS
cell differentiation	P		IEA
blood vessel morphogenesis	P		IMP	ISS
lung development	P		IMP IMP IDA	ISS
cell proliferation	P	IEA	IMP	ISS IEA
mRNA stabilization	P			IDA
vasculogenesis	P			ISS
anti-apoptosis	P		IMP	ISS
signal transduction	P			ISS
eye photoreceptor cell development	P		IMP	ISS
mesoderm development	P		IMP	ISS
positive regulation of transcription from RNA polymerase II promoter	P			IDA
angiogenesis	P		IDA IDA IMP IMP IMP IGI	TAS ISS ISS IMP
vascular endothelial growth factor receptor signaling pathway	P		IDA
positive regulation of smooth muscle cell proliferation	P			IMP
alveolus development	P			IMP
cell migration	P		IDA IGI	ISS ISS
blood vessel remodeling	P			IMP
patterning of blood vessels	P		IMP
multicellular organismal development	P		IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (23)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
skin/coat/nails phenotype	MP		Un
cellular phenotype	MP		Un
craniofacial phenotype	MP		Un Un Un
behavior/neurological phenotype	MP		Un Un
endocrine/exocrine gland phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un Un
immune system phenotype	MP		Un
embryogenesis phenotype	MP		Un Un Un
lethality-embryonic/perinatal	MP		Un Un Un Un
skeleton phenotype	MP		Un
lethality-postnatal	MP		Un
muscle phenotype	MP		Un
renal/urinary system phenotype	MP		Un Un
nervous system phenotype	MP		Un Un
vision/eye phenotype	MP		Un Un
normal phenotype	MP		Un
digestive/alimentary phenotype	MP		Un
cardiovascular system phenotype	MP		Un Un Un
limbs/digits/tail phenotype	MP		Un
reproductive system phenotype	MP		Un
hematopoietic system phenotype	MP		Un Un
liver/biliary system phenotype	MP		Un
growth/size phenotype	MP		Un Un Un

Disease (18)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
??	D			IEP
Multiple Sclerosis	D			ISS
Intracranial Arteriovenous Malformations	D			ISS
Alzheimer Disease	D			ISS
Mucocutaneous Lymph Node Syndrome	D			ISS
Myocardial Diseases	D			ISS
Amyotrophic Lateral Sclerosis	D			ISS
Pre-Eclampsia	D			ISS
Heart Defects, Congenital	D			ISS
Sudden Infant Death	D			ISS
Encephalomyelitis, Experimental Autoimmune	D			IED
Retinal Neovascularization	D			IED
Pulmonary Edema	D			IED
Colitis, Ischemic	D			ISS
Coronary Arteriosclerosis	D			ISS
Diabetic Retinopathy	D			ISS
Brain Edema	D			IED
Hypertension	D			ISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
vascular endothelial growth factor signaling pathway	W			IDAIMP
the chronic hypoxic response - the hypoxia inducible factor - alpha pathway	W			IDA

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
mTOR signaling pathway (04150)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
VEGF signaling pathway (04370)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cytokine-cytokine receptor interaction (04060)	Present in KEGG pathway	Present in KEGG pathway	Not present in KEGG pathway
Pancreatic cancer (05212)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway