IpiRecord: IPI00555993

IPI00555993 - FLT4, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3 VARIANT (FRAGMENT).
Uniprot Accession: Q59F24
Uniprot ID: Q59F24_HUMAN
Mapping: Chr 5, 179962143 - 180009171
Entrez Gene: 2324
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_9344)
Rat: Flt4, ISOFORM 1 OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3 PRECURSOR.
Mouse: Flt4, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3 PRECURSOR.
Rat: Flt4, ISOFORM 2 OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3 PRECURSOR.
Human: FLT4, FMS-RELATED TYROSINE KINASE 4 ISOFORM 1.
Human: FLT4, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3 PRECURSOR.
Human: FLT4, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3 VARIANT (FRAGMENT).
Human: FLT4, FLT4 PROTEIN (FRAGMENT).

Annotations for FLT4 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to plasma membraneCTAS ISS 
membraneCIEA IEA IEA 
extracellular spaceCRCA ISS 
integral to membraneCIEA RCA ISS 
ATP bindingFIEA IEA IEA 
transmembrane receptor protein tyrosine kinase activityFIEA 
kinase activityFIEA 
protein bindingFIPI IPI IPI ISS 
protein-tyrosine kinase activityFIEA IEA IEA 
growth factor bindingFIMP 
protein serine/threonine kinase activityFISS 
nucleotide bindingFIEA IEA 
receptor activityFIEA IEA 
transferase activityFIEA IEA 
vascular endothelial growth factor receptor activityFIEA IDA ISS IGI IMP ISS 
protein kinase activityFIEA 
transmembrane receptor protein tyrosine kinase signaling pathwayPIEA IEA ISS 
protein amino acid phosphorylationPIEA IEA 
positive regulation of cell proliferationPIGI ISS IGI 
lymphangiogenesisPISS 
vascular endothelial growth factor receptor signaling pathwayPIGI IDA ISS IMP 
positive regulation of cell growthPIDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (13)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
adipose tissue phenotypeMPUn
homeostasis/metabolism phenotypeMPUn Un
immune system phenotypeMPUn Un
embryogenesis phenotypeMPUn Un
lethality-embryonic/perinatalMPUn Un
growth/size phenotypeMPUn Un
liver/biliary system phenotypeMPUn
cardiovascular system phenotypeMPUn Un
digestive/alimentary phenotypeMPUn
reproductive system phenotypeMPUn
lethality-postnatalMPUn
edemaNIEA

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
altered vascular endothelial growth factor signaling pathwayWISS
vascular endothelial growth factor signaling pathwayWIMP
altered vascular endothelial growth factor signaling pathway involving the main playersWISS

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway