IPI report for IPI00556163

IpiRecord: IPI00556163

IPI00556163 - CFLAR, CASP8 AND FADD-LIKE APOPTOSIS REGULATOR VARIANT (FRAGMENT).
Uniprot Accession: Q59F61
Uniprot ID: Q59F61_HUMAN
Mapping: Chr 2, 201689135 - 201737246
Entrez Gene: 8837
Entrez MapView:
+All IPI Database Cross References UniProtKB/TrEMBL: Q59F61 UniProtKB/TrEMBL: Q59F61_HUMAN ENSEMBL: ENSP00000363789 ENSEMBL: ENSG00000003402 UniParc: UPI00004F6D72 HGNC: 1876 Entrez Gene: 8837 UniGene: Hs.390736 UTRdb: BB001228 UTRdb: BB002970 UTRdb: BB009296 UTRdb: BB042984 UTRdb: BB046980 UTRdb: BB349336 UTRdb: BB349337 UTRdb: BB352091 UTRdb: BB387407 UTRdb: CC390261 RZPD: Hs.390736 InterPro: IPR011029 InterPro: IPR001875 InterPro: IPR002398 Pfam: PF01335 SMART: SM00031 PROSITE: PS50168 SUPERFAMILY: SSF47986 PANTHER: PTHR10454 GENE3D: G3DSA:1.10.533.10

IPI00556163 - CFLAR, CASP8 AND FADD-LIKE APOPTOSIS REGULATOR VARIANT (FRAGMENT).

Uniprot Accession: Q59F61

Uniprot ID: Q59F61_HUMAN

Mapping: Chr 2, 201689135 - 201737246

Entrez Gene: 8837

Entrez MapView: Geneprod

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_17701)
Rat: Cflar, CASP8 AND FADD-LIKE APOPTOSIS REGULATOR.
Human: CFLAR, ISOFORM 1 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.
Human: CFLAR, ISOFORM 2 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.
Human: CFLAR, ISOFORM 3 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.
Human: CFLAR, ISOFORM 4 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.
Human: CFLAR, ISOFORM 5 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.
Human: CFLAR, ISOFORM 6 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.
Human: CFLAR, ISOFORM 8 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.
Human: CFLAR, ISOFORM 9 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.
Human: CFLAR, ISOFORM 10 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.
Human: CFLAR, ISOFORM 12 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.
Human: CFLAR, ISOFORM 13 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.
Human: CFLAR, ISOFORM 14 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.
Human: CFLAR, ISOFORM 11 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.
Human: CFLAR, ISOFORM 7 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.
Human: CFLAR, CASP8 AND FADD-LIKE APOPTOSIS REGULATOR VARIANT (FRAGMENT).
Rat: Cflar, CASP8 AND FADD-LIKE APOPTOSIS REGULATOR ISOFORM 2.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_17701)

Rat: Cflar, CASP8 AND FADD-LIKE APOPTOSIS REGULATOR.

Human: CFLAR, ISOFORM 1 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.

Human: CFLAR, ISOFORM 2 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.

Human: CFLAR, ISOFORM 3 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.

Human: CFLAR, ISOFORM 4 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.

Human: CFLAR, ISOFORM 5 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.

Human: CFLAR, ISOFORM 6 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.

Human: CFLAR, ISOFORM 8 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.

Human: CFLAR, ISOFORM 9 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.

Human: CFLAR, ISOFORM 10 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.

Human: CFLAR, ISOFORM 12 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.

Human: CFLAR, ISOFORM 13 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.

Human: CFLAR, ISOFORM 14 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.

Human: CFLAR, ISOFORM 11 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.

Human: CFLAR, ISOFORM 7 OF CASP8 AND FADD-LIKE APOPTOSIS REGULATOR PRECURSOR.

Human: CFLAR, CASP8 AND FADD-LIKE APOPTOSIS REGULATOR VARIANT (FRAGMENT).

Rat: Cflar, CASP8 AND FADD-LIKE APOPTOSIS REGULATOR ISOFORM 2.

Annotations for CFLAR and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Rat
cytoplasm	C		ISS
protein binding	F	IEA	IEA
caspase activity	F	IEA	IEA
negative regulation of caspase activity	P		ISS
regulation of apoptosis	P	IEA	ISS IEA
negative regulation of apoptosis	P		ISS
apoptosis	P		ISS
anti-apoptosis	P		IMP
proteolysis	P	IEA	IEA

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Apoptosis (04210)	Present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway