IpiRecord: IPI00639876

IPI00639876 - FYN, UNCHARACTERIZED PROTEIN FYN.
Uniprot Accession: Q5R3A8
Uniprot ID: Q5R3A8_HUMAN
Mapping: Chr 6, 112088228 - 112301348
Entrez Gene: 2534
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14572)
Rat: Fyn, 60 KDA PROTEIN.
Mouse: Fyn, ISOFORM 2 OF PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN.
Mouse: Fyn, ISOFORM 1 OF PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN.
Rat: Fyn, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN.
Human: FYN, ISOFORM 3 OF PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN.
Human: FYN, ISOFORM 1 OF PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN.
Human: FYN, UNCHARACTERIZED PROTEIN FYN.
Human: FYN, ISOFORM 2 OF PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN.

Annotations for FYN and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
mitochondrial envelopeCIEP 
membraneCIEA 
protein kinase activityFIDA ISS 
metal ion bindingFIEA IEA 
kinase activityFIEA TAS 
protein bindingFIPI IPI ISS IDA 
identical protein bindingFISS 
ATP bindingFIEA IEA IEA IEA 
protein-tyrosine kinase activityFIEA IDA IDA IDA ISS ISS IEA 
manganese ion bindingFIEA IEA 
transferase activityFIEA IEA 
tubulin bindingFIDA ISS 
nucleotide bindingFIEA IEA 
neuron migrationPIGI IMP ISS 
intracellular signaling cascadePIEA IEA IEA 
peptidyl-tyrosine phosphorylationPIDA IDA ISS IMP ISS 
feeding behaviorPISS ISS 
protein amino acid phosphorylationPIEA IEA ISS IEA 
forebrain developmentPIGI IMP ISS 
regulation of neuronal synaptic plasticityPISS 
visual learningPISS 
learningPISS 
protein kinase cascadePISS 
ionotropic glutamate receptor signaling pathwayPTAS 
regulation of cell shapePIDA ISS 
myelinationPTAS ISS ISS 
multicellular organismal developmentPIEA IEA 
T cell receptor signaling pathwayPISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (17)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
behavior/neurological phenotypeMPUn Un
homeostasis/metabolism phenotypeMPUn Un
immune system phenotypeMPUn Un
life span-post-weaning/agingMPUn Un
lethality-postnatalMPUn
taste/olfaction phenotypeMPUn
reproductive system phenotypeMPUn Un
nervous system phenotypeMPUn Un Un
growth/size phenotypeMPUn
vision/eye phenotypeMPUn
hearing/vestibular/ear phenotypeMPUn
hematopoietic system phenotypeMPUn Un
renal/urinary system phenotypeMPUn
reduced kindling behaviorNIEA
abnormal nursingNIEA

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
??DISS
Alzheimer DiseaseDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pathogenic Escherichia coli infection - EHEC (05130)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Adherens junction (04520)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pathogenic Escherichia coli infection - EPEC (05131)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
Axon guidance (04360)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway