| IPI00641659 - ROCK1, 158 KDA PROTEIN. | |
|---|---|
| Uniprot Accession: -NA- | |
| Uniprot ID: -NA- | |
| Mapping: Chr 18, 16787533 - 16944869 | |
| Entrez Gene: 6093 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13443) |
|---|
| Rat: Rock1, ISOFORM 1 OF RHO-ASSOCIATED PROTEIN KINASE 1. |
| Mouse: Rock1, ISOFORM 1 OF RHO-ASSOCIATED PROTEIN KINASE 1. |
| Mouse: Rock1, ISOFORM 2 OF RHO-ASSOCIATED PROTEIN KINASE 1. |
| Rat: Rock1, ISOFORM 2 OF RHO-ASSOCIATED PROTEIN KINASE 1. |
| Rat: Rock1, 158 KDA PROTEIN. |
| Human: ROCK1, RHO-ASSOCIATED PROTEIN KINASE 1. |
| Human: ROCK1, 20 KDA PROTEIN. |
| Human: ROCK1, 158 KDA PROTEIN. |
| Human: ROCK1, 22 KDA PROTEIN. |
| Human: ROCK1, 9 KDA PROTEIN. |
| Human: ROCK1, 11 KDA PROTEIN. |
| Human: ROCK1, ROCK1 PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| microtubule | C | ISS | ||
| Golgi apparatus | C | IEA | IEA | |
| cytoskeleton | C | IEA | IEA | |
| membrane | C | IEA | IEA | |
| intracellular | C | IEA | IEA | |
| cytoplasm | C | IEA | IEA | |
| structural molecule activity | F | RCA | ISS | |
| diacylglycerol binding | F | IEA | IEA | |
| GTP-Rho binding | F | IMP | ||
| identical protein binding | F | IPI | ||
| nucleotide binding | F | IEA | IEA | |
| protein serine/threonine kinase activity | F | TAS IEA | IEA IEA | NAS ISS |
| protein-tyrosine kinase activity | F | ISS | ||
| metal ion binding | F | IEA | IEA | |
| zinc ion binding | F | IEA | IEA | |
| ATP binding | F | IEA | IEA IEA | |
| transferase activity | F | IEA | IEA | |
| protein binding | F | IEA | IPI | |
| protein kinase activity | F | IEA | IEA | |
| kinase activity | F | IEA | ||
| protein amino acid phosphorylation | P | TAS IEA | IEA | ISS |
| actin cytoskeleton organization and biogenesis | P | TAS | IGI | ISS |
| cytokinesis | P | IEA | IEA | |
| apoptosis | P | IEA | IEA | |
| Rho protein signal transduction | P | TAS | ISS | |
| intracellular signaling cascade | P | IEA | IEA | |
| signal transduction | P | IEA | IEA | |
| negative regulation of neuron apoptosis | P | IEA | IMP | ISS |
| cytoskeleton organization and biogenesis | P | IMP | ||
| microtubule-based movement | P | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un | ||
| lethality-postnatal | MP | Un | ||
| vision/eye phenotype | MP | Un | ||
| normal phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Pathogenic Escherichia coli infection - EHEC (05130) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| TGF-beta signaling pathway (04350) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pathogenic Escherichia coli infection - EPEC (05131) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Leukocyte transendothelial migration (04670) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Wnt signaling pathway (04310) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Axon guidance (04360) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |