IpiRecord: IPI00647613

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
integral to plasma membrane	C	ISS ISS
focal adhesion	C	ISS ISS	IDA
external side of plasma membrane	C		IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA	ISS
integral to membrane	C		RCA	ISS
membrane	C		IEA
internal side of plasma membrane	C			TAS
receptor activity	F	IEA	IEA
protein binding	F		IPI	ISS
phosphoric monoester hydrolase activity	F	IEA	IEA
protein kinase binding	F	ISS ISS	IPI	ISS
transmembrane receptor protein tyrosine phosphatase activity	F			TAS ISS
phosphoprotein phosphatase activity	F		IEA
protein kinase regulator activity	F			TAS
hydrolase activity	F	IEA	IEA	IEA
protein tyrosine phosphatase activity	F	ISS ISS IEA	IEA IEA
T cell proliferation	P		IMP	ISS
negative regulation of cytokine and chemokine mediated signaling pathway	P	ISS ISS	IDA
B cell receptor signaling pathway	P	ISS ISS	IMP
dephosphorylation	P		IEA
B cell differentiation	P		IMP	ISS
cell surface receptor linked signal transduction	P			ISS
response to gamma radiation	P			IDA
protein amino acid dephosphorylation	P	ISS ISS IEA	IDA	TAS IEA
negative regulation of protein kinase activity	P	ISS ISS	IDA	ISS
T cell receptor signaling pathway	P	ISS ISS		ISS
positive regulation of antigen receptor-mediated signaling pathway	P	ISS ISS	IMP
T cell differentiation	P	ISS ISS	IMP	ISS
B cell proliferation	P	ISS ISS	IMP	ISS
regulation of cell cycle	P	ISS ISS	IDA
defense response to virus	P	ISS ISS	IMP
negative regulation of T cell mediated cytotoxicity	P	ISS ISS	IMP
positive regulation of T cell proliferation	P	ISS ISS	IMP
release of sequestered calcium ion into cytosol	P	ISS ISS	IDA
positive regulation of protein kinase activity	P			ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
homeostasis/metabolism phenotype	MP		Un
immune system phenotype	MP		Un Un Un Un
lethality-postnatal	MP		Un
renal/urinary system phenotype	MP		Un
tumorigenesis	MP		Un
digestive/alimentary phenotype	MP		Un
normal phenotype	MP		Un
hematopoietic system phenotype	MP		Un Un Un Un
life span-post-weaning/aging	MP		Un

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Severe Combined Immunodeficiency	D			ISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
T cell receptor signaling pathway (04660)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cell adhesion molecules (CAMs) (04514)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway