IpiRecord: IPI00656051

IPI00656051 - IKBKB, IKBKB PROTEIN.
Uniprot Accession: Q32ND9
Uniprot ID: Q32ND9_HUMAN
Mapping: Chr 8, 42247986 - 42309130
Entrez Gene: 3551
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12951)
Rat: Ikbkb, INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT BETA.
Mouse: Ikbkb, INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT BETA.
Mouse: Ikbkb, FULL INSERT SEQUENCE.
Mouse: Ikbkb, IKBKB PROTEIN.
Mouse: Ikbkb, SEQUENCE.
Mouse: Ikbkb, SEQUENCE.
Mouse: Ikbkb, 4 KDA PROTEIN.
Mouse: Ikbkb, PROTEIN.
Rat: Ikbkb, 25 KDA PROTEIN.
Human: IKBKB, INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT BETA.
Human: IKBKB, BETA VARIANT (FRAGMENT).
Human: IKBKB, IKBKB PROTEIN.
Human: IKBKB, 5 KDA PROTEIN.
Human: IKBKB, 19 KDA PROTEIN.
Human: IKBKB, IKBKB PROTEIN.
Human: IKBKB, 18 KDA PROTEIN.
Human: IKBKB, 25 KDA PROTEIN.
Human: IKBKB, 29 KDA PROTEIN.

Annotations for IKBKB and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCNAS TAS ISS ISS IDA 
identical protein bindingFIPI IPI 
protein bindingFISS ISS IDA 
ATP bindingFNAS IEA IEA IEA ISS IEA IDA 
protein serine/threonine kinase activityFNAS IEA IEA IEA ISS IEA 
protein-tyrosine kinase activityFIEA RCA ISS IEA 
protein kinase activityFIEA IMP IDA IMP ISS IDA 
transferase activityFIEA IEA IEA 
receptor signaling protein serine/threonine kinase activityFTAS ISS 
kinase activityFIEA IDA 
transcription activator activityFNAS NAS NAS ISS 
nucleotide bindingFIEA IEA IEA 
protein amino acid phosphorylationPNAS IEA IEA ISS IEA 
B cell homeostasisPIMP ISS 
activation of NF-kappaB transcription factorPIDA ISS ISS IMP 
regulation of I-kappaB kinase/NF-kappaB cascadePIMP 
I-kappaB phosphorylationPTAS ISS IDA IMP 
protein modification processPIEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (12)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn Un Un Un
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn Un Un Un
lethality-embryonic/perinatalMPUn Un Un Un
lethality-postnatalMPUn
nervous system phenotypeMPUn
cardiovascular system phenotypeMPUn
limbs/digits/tail phenotypeMPUn
digestive/alimentary phenotypeMPUn Un
normal phenotypeMPUn Un
hematopoietic system phenotypeMPUn
liver/biliary system phenotypeMPUn Un Un Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Epithelial cell signaling in Helicobacter pylori infection (05120)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Adipocytokine signaling pathway (04920)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Type II diabetes mellitus (04930)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Insulin signaling pathway (04910)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway