IpiRecord: IPI00745564

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
nucleolus	C			IDA
nuclear body	C	IEA	IDA
cytoplasm	C			IDA
spindle	C	IEA	IDA	ISS IEA
nucleus	C	IEA IDA	IDA ISS	TAS ISS ISS IDA IDA IEA
sequence-specific DNA binding	F			IDA
double-stranded DNA binding	F			IDA
transcription factor activity	F	IEA TAS	IEA	ISS IEA IDA
DNA binding	F		IDA IDA	IDA ISS
transcription regulator activity	F		IEA
protein binding	F	IPI IPI IPI IPI	IPI IPI ISS	ISS ISS IEA
response to radiation	P	IEA	IDA IMP	ISS IEA
regulation of transcription	P		IGI
regulation of apoptosis	P	IEA	IDA	ISS IEA
cellular process	P		IEA
transcription initiation	P			IDA
regulation of progression through mitotic cell cycle	P			IMP
regulation of progression through cell cycle	P		IEA
caspase activation	P	IEA	IDA	ISS IEA
DNA fragmentation during apoptosis	P	IEA	IDA	ISS IEA
positive regulation of cell proliferation	P	IDA	ISS	ISS IEA
activation of pro-apoptotic gene products	P	IEA	IDA IMP	ISS IEA
induction of apoptosis by intracellular signals	P	IEA	IDA IMP	ISS IEA
glucose metabolic process	P			IMP
cell proliferation	P			ISS
cell cycle arrest	P	TAS		ISS
transcription, DNA-dependent	P			IDA
regulation of cell proliferation	P		IDA IDA	ISS
transcription	P		IEA
pathogenesis	P			TAS
cellular iron ion homeostasis	P	TAS		ISS
transcription from RNA polymerase II promoter	P			IDA
regulation of transcription, DNA-dependent	P	IEA	IEA IEA	TAS IDA IEA
regulation of transcription from RNA polymerase II promoter	P	TAS		ISS
negative regulation of survival gene product activity	P	IEA	IDA IMP	ISS IEA
positive regulation of transcription from RNA polymerase II promoter	P			IMP
release of cytochrome c from mitochondria	P	IEA	IDA	ISS IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (13)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
immune system phenotype	MP		Un Un
embryogenesis phenotype	MP		Un
lethality-embryonic/perinatal	MP		Un Un
muscle phenotype	MP		Un
nervous system phenotype	MP		Un
tumorigenesis	MP		Un
cardiovascular system phenotype	MP		Un
normal phenotype	MP		Un Un
hematopoietic system phenotype	MP		Un Un
reproductive system phenotype	MP		Un
life span-post-weaning/aging	MP		Un
no phenotypic analysis	MP		Un
growth/size phenotype	MP		Un Un

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Burkitt Lymphoma	D			ISS
Multiple Myeloma	D			ISS
Leukemia, Plasmacytic	D			ISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Chronic myeloid leukemia (05220)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
TGF-beta signaling pathway (04350)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
MAPK signaling pathway (04010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Wnt signaling pathway (04310)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Colorectal cancer (05210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway