IpiRecord: IPI00792701

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
plasma membrane	C		TAS	ISS
mitochondrial outer membrane	C	TAS		ISS
insoluble fraction	C			IDA
intracellular	C		IEA
cytosol	C		TAS	TAS ISS
metal ion binding	F	IEA	IEA	IEA
protein heterodimerization activity	F			IPI
diacylglycerol binding	F	IEA	IEA	IEA
protein binding	F	IPI IPI	IPI IPI	ISS ISS IEA
MAP kinase kinase kinase activity	F			TAS IMP IDA
ATP binding	F	IEA	IEA IEA	IEA
protein serine/threonine kinase activity	F	IEA	IEA IEA	IEA
protein kinase activity	F	IEA	TAS	ISS
nucleotide binding	F	IEA	IEA	IEA
transferase activity	F	IEA	IEA	IEA
kinase activity	F		IEA
receptor signaling protein activity	F	IEA	IEA	IEA
mitogen-activated protein kinase kinase binding	F			IMP
zinc ion binding	F	IEA	IEA	IEA
regulation of progression through cell cycle	P		IEA
response to hypoxia	P			IDA
intracellular signaling cascade	P	IEA	IEA	IEA
cell proliferation	P	TAS		ISS
apoptosis	P	TAS	IMP IGI	ISS ISS IEA
protein amino acid phosphorylation	P	TAS IEA	IEA	TAS IMP ISS IEA
MAPKKK cascade	P			IDA
cellular process	P		IEA
nerve growth factor receptor signaling pathway	P	IEA	IMP
cytoskeleton organization and biogenesis	P	IEA	IMP	ISS IEA
protein kinase cascade	P		TAS	TAS ISS
heart development	P			IEP
signal transduction	P		IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (12)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un Un Un
embryogenesis phenotype	MP		Un Un
lethality-embryonic/perinatal	MP		Un Un Un Un
lethality-postnatal	MP		Un
muscle phenotype	MP		Un
nervous system phenotype	MP		Un Un
growth/size phenotype	MP		Un Un Un
cardiovascular system phenotype	MP		Un Un
liver/biliary system phenotype	MP		Un Un
hematopoietic system phenotype	MP		Un
normal phenotype	MP		Un Un
abnormal apoptosis	N			ISS

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Ischemia	D			ISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
The extracellular signal-regulated RAF/MEK/ERK pathway	W			IMPTASIMP

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Glioma (05214)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
GnRH signaling pathway (04912)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Long-term depression (04730)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Chronic myeloid leukemia (05220)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Fc epsilon RI signaling pathway (04664)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
MAPK signaling pathway (04010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
VEGF signaling pathway (04370)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Colorectal cancer (05210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Regulation of actin cytoskeleton (04810)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Gap junction (04540)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Dorso-ventral axis formation (04320)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Pancreatic cancer (05212)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Insulin signaling pathway (04910)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Long-term potentiation (04720)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway