| IPI00793270 - PTK2, PTK2 PROTEIN. | |
|---|---|
| Uniprot Accession: Q8IYN9 | |
| Uniprot ID: Q8IYN9_HUMAN | |
| Mapping: Chr 8, 141737683 - 142080514 | |
| Entrez Gene: 5747 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7347) |
|---|
| Rat: Ptk2, 58 KDA PROTEIN. |
| Mouse: Ptk2, ISOFORM 1 OF FOCAL ADHESION KINASE 1. |
| Mouse: Ptk2, ISOFORM 2 OF FOCAL ADHESION KINASE 1. |
| Mouse: Ptk2, FOCAL ADHESION KINASE SPLICED VARIANT P110FAK. |
| Mouse: Ptk2, FOCAL ADHESION KINASE. |
| Mouse: Ptk2, SEQUENCE. |
| Rat: Ptk2, FOCAL ADHESION KINASE 1. |
| Rat: Ptk2, 124 KDA PROTEIN. |
| Human: PTK2, ISOFORM 1 OF FOCAL ADHESION KINASE 1. |
| Human: PTK2, ISOFORM 3 OF FOCAL ADHESION KINASE 1. |
| Human: PTK2, ISOFORM 4 OF FOCAL ADHESION KINASE 1. |
| Human: PTK2, PTK2 PROTEIN TYROSINE KINASE 2 ISOFORM B. |
| Human: PTK2, PTK2 PROTEIN TYROSINE KINASE 2 ISOFORM B VARIANT. |
| Human: PTK2, PTK2 PROTEIN. |
| Human: PTK2, 14 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cell junction | C | IEA | ||
| cytoskeleton | C | IEA | IEA | ISS IEA |
| apical plasma membrane | C | IDA | ||
| lamellipodium | C | IDA | ISS | |
| focal adhesion | C | IEA | IDA IDA IDA IDA | TAS ISS |
| protein serine/threonine kinase activity | F | ISS | ||
| ATP binding | F | IEA | IEA IEA | IEA |
| protein binding | F | IPI IPI | ISS ISS IDA | |
| kinase activity | F | IEA | ||
| protein-tyrosine kinase activity | F | IEA | IEA IEA | TAS ISS IEA |
| protein kinase activity | F | IEA | ||
| SH2 domain binding | F | ISS | ||
| transferase activity | F | IEA | IEA | IEA |
| signal transducer activity | F | IEA | ||
| nucleotide binding | F | IEA | IEA | IEA |
| establishment of nucleus localization | P | IDA | ISS | |
| neuron migration | P | IDA IMP | ISS | |
| extracellular matrix organization and biogenesis | P | IMP | ISS | |
| cell motility | P | TAS | ISS | |
| protein amino acid phosphorylation | P | IEA | IEA | ISS IEA |
| microtubule cytoskeleton organization and biogenesis | P | IDA | ISS | |
| endothelial cell migration | P | IMP | ||
| angiogenesis | P | IMP | ||
| integrin-mediated signaling pathway | P | TAS | ISS ISS | |
| negative regulation of organ size | P | IGI | ISS | |
| signal complex assembly | P | IEA | ||
| blood vessel development | P | IMP IMP | ISS | |
| vasculogenesis | P | IMP | ||
| protein amino acid autophosphorylation | P | IMP |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un Un Un | ||
| skin/coat/nails phenotype | MP | Un Un Un Un | ||
| endocrine/exocrine gland phenotype | MP | Un Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un Un Un | ||
| lethality-embryonic/perinatal | MP | Un Un Un | ||
| muscle phenotype | MP | Un Un | ||
| nervous system phenotype | MP | Un Un | ||
| tumorigenesis | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| normal phenotype | MP | Un Un | ||
| cardiovascular system phenotype | MP | Un Un Un | ||
| hematopoietic system phenotype | MP | Un | ||
| growth/size phenotype | MP | Un Un Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Hypertension, Pulmonary | D | ISS | ||
| Hypertension | D | IAGP |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| VEGF signaling pathway (04370) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Leukocyte transendothelial migration (04670) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Axon guidance (04360) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |