IpiRecord: IPI00793550

IPI00793550 - GRIN1, UNCHARACTERIZED PROTEIN GRIN1.
Uniprot Accession: A6NED8
Uniprot ID: A6NED8_HUMAN
Mapping: Chr 9, 139152663 - 139183028
Entrez Gene: 2902
Entrez MapView:
+All IPI Database Cross References UniProtKB/TrEMBL: A6NED8 UniProtKB/TrEMBL: A6NED8_HUMAN ENSEMBL: ENSP00000360605 ENSEMBL: ENSG00000176884 UniParc: UPI0000458B10 HGNC: 4584 Entrez Gene: 2902 UniGene: Hs.558334 UTRdb: BB006688 UTRdb: BB057358 UTRdb: BB382059 UTRdb: CC007280 UTRdb: CC007283 UTRdb: CC389267 UTRdb: CC389424 RZPD: Hs.558334 InterPro: IPR001828 InterPro: IPR015683 InterPro: IPR001320 InterPro: IPR001508 Pfam: PF01094 Pfam: PF00060 PRINTS: PR00177 SMART: SM00079 PANTHER: PTHR18966

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2994)
Rat: Grin1, ISOFORM A OF GLUTAMATE [NMDA] RECEPTOR SUBUNIT ZETA-1 PRECURSOR.
Mouse: Grin1, ISOFORM 1 OF GLUTAMATE [NMDA] RECEPTOR SUBUNIT ZETA-1 PRECURSOR.
Mouse: Grin1, ISOFORM 2 OF GLUTAMATE [NMDA] RECEPTOR SUBUNIT ZETA-1 PRECURSOR.
Mouse: Grin1, GLUTAMATE RECEPTOR IONOTROPIC NMDA1.
Mouse: Grin1, GLUTAMATE RECEPTOR IONOTROPIC NMDA1.
Mouse: Grin1, GLUTAMATE RECEPTOR IONOTROPIC NMDA1.
Mouse: Grin1, GLUTAMATE RECEPTOR IONOTROPIC NMDA1.
Mouse: Grin1, GLUTAMATE RECEPTOR IONOTROPIC NMDA1.
Mouse: Grin1, GLUTAMATE RECEPTOR IONOTROPIC NMDA1.
Rat: Grin1, ISOFORM B OF GLUTAMATE [NMDA] RECEPTOR SUBUNIT ZETA-1 PRECURSOR.
Rat: Grin1, ISOFORM C OF GLUTAMATE [NMDA] RECEPTOR SUBUNIT ZETA-1 PRECURSOR.
Rat: Grin1, ISOFORM D OF GLUTAMATE [NMDA] RECEPTOR SUBUNIT ZETA-1 PRECURSOR.
Rat: Grin1, ISOFORM E OF GLUTAMATE [NMDA] RECEPTOR SUBUNIT ZETA-1 PRECURSOR.
Rat: Grin1, ISOFORM G OF GLUTAMATE [NMDA] RECEPTOR SUBUNIT ZETA-1 PRECURSOR.
Rat: Grin1, ISOFORM F OF GLUTAMATE [NMDA] RECEPTOR SUBUNIT ZETA-1 PRECURSOR.
Human: GRIN1, ISOFORM 2 OF GLUTAMATE [NMDA] RECEPTOR SUBUNIT ZETA-1 PRECURSOR.
Human: GRIN1, ISOFORM 3 OF GLUTAMATE [NMDA] RECEPTOR SUBUNIT ZETA-1 PRECURSOR.
Human: GRIN1, ISOFORM 1 OF GLUTAMATE [NMDA] RECEPTOR SUBUNIT ZETA-1 PRECURSOR.
Human: GRIN1, GLUTAMATE RECEPTOR, IONOTROPIC, N-METHYL D-ASPARTATE 1.
Human: GRIN1, ISOFORM 4 OF GLUTAMATE [NMDA] RECEPTOR SUBUNIT ZETA-1 PRECURSOR.
Human: GRIN1, ISOFORM 5 OF GLUTAMATE [NMDA] RECEPTOR SUBUNIT ZETA-1 PRECURSOR.
Human: GRIN1, GLUTAMATE RECEPTOR, IONOTROPIC, N-METHYL D-ASPARTATE 1.
Human: GRIN1, GLUTAMATE RECEPTOR, IONOTROPIC, N-METHYL D-ASPARTATE 1.
Human: GRIN1, GLUTAMATE RECEPTOR, IONOTROPIC, N-METHYL D-ASPARTATE 1.
Human: GRIN1, UNCHARACTERIZED PROTEIN GRIN1.
Human: GRIN1, UNCHARACTERIZED PROTEIN GRIN1.
Human: GRIN1, UNCHARACTERIZED PROTEIN GRIN1.
Human: GRIN1, UNCHARACTERIZED PROTEIN GRIN1.

Annotations for GRIN1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
cell junction	C	IEA	IEA
membrane	C	IEA	IEA IEA
cytoplasm	C		IDA	ISS
synaptic vesicle	C		IDA	ISS
N-methyl-D-aspartate selective glutamate receptor complex	C	ISS		TAS ISS
membrane fraction	C		IDA IDA	ISS
synapse	C	IEA	ISS ISS
growth cone	C		NAS
dendrite	C	ISS		ISS
postsynaptic membrane	C	IEA	IDA IDA	ISS
integral to membrane	C	IEA	IEA
extracellular-glycine-gated ion channel activity	F			ISS
ionotropic glutamate receptor activity	F	IEA	IEA	TAS
magnesium ion binding	F		IEA
calcium ion binding	F		IEA
extracellular-glutamate-gated ion channel activity	F	IEA	IEA
ion channel activity	F	IEA	IEA IEA
N-methyl-D-aspartate selective glutamate receptor activity	F			TAS ISS
receptor activity	F	IEA	IEA IEA
receptor binding	F		IDA	ISS
glutamate binding	F			ISS
potassium channel activity	F		RCA	ISS
protein binding	F		IPI IPI	ISS
glycine binding	F		NAS	ISS
motor activity	F			ISS
response to ethanol	P		NAS
visual learning	P		IGI
potassium ion transport	P		RCA	ISS
learning and/or memory	P			TAS ISS
synaptic transmission	P		TAS	ISS ISS
cation transport	P			ISS
transport	P		IEA
cellular calcium ion homeostasis	P			ISS
ion transport	P	IEA	IEA IEA
regulation of synaptic plasticity	P			ISS
glutamate signaling pathway	P			ISS

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (13)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Mouse	Rat
growth/size phenotype	MP	Un Un Un Un
behavior/neurological phenotype	MP	Un Un Un Un Un Un Un Un Un
homeostasis/metabolism phenotype	MP	Un Un Un Un
lethality-embryonic/perinatal	MP	Un Un Un Un
lethality-postnatal	MP	Un Un
nervous system phenotype	MP	Un Un Un Un Un Un
reproductive system phenotype	MP	Un Un
normal phenotype	MP	Un
cardiovascular system phenotype	MP	Un
hearing/vestibular/ear phenotype	MP	Un
respiratory system phenotype	MP	Un Un Un Un
hypoactivity	N		IEA
abnormal spatial learning	N		IEA

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Alcoholism	D			ISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
Excitatory synaptic transmission pathway	W			IDA

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Neuroactive ligand-receptor interaction (04080)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Calcium signaling pathway (04020)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Long-term potentiation (04720)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway