IpiRecord: IPI00793815

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
membrane	C		IEA	IEA
intrinsic to membrane	C	IEA
cytoplasm	C	IEA	TAS	ISS
protein binding	F	IEA IPI IPI IPI IPI	IPI
signal transducer activity	F	IEP
death receptor binding	F	TAS
Toll binding	F			IDA
transmembrane receptor activity	F	IEA	IEA	IEA
receptor binding	F			IPI
activation of NF-kappaB transcription factor	P	IEA	IGI IMP
inflammatory response	P	IEA	IEA
cytokine and chemokine mediated signaling pathway	P			IMP
Toll signaling pathway	P			IDA
cell surface receptor linked signal transduction	P		IMP	ISS
immune response	P		TAS	ISS
positive regulation of chemokine biosynthetic process	P	IEA	IGI
response to virus	P	IEA	IMP IMP	ISS
MyD88-dependent toll-like receptor signaling pathway	P	IEA	IMP IGI
immunoglobulin mediated immune response	P	IEA	IMP	ISS
positive regulation of JNK cascade	P	IEA	IMP
response to lipopolysaccharide	P	IEA	IMP IMP IGI IMP
signal transduction	P	IEA	IEA	IEA
innate immune response	P	IEA
lipopolysaccharide-mediated signaling pathway	P	IEA	IMP
I-kappaB kinase/NF-kappaB cascade	P			ISS
transmembrane receptor protein serine/threonine kinase signaling pathway	P		TAS	ISS
response to molecule of fungal origin	P	IEA	IMP
positive regulation of transcription from RNA polymerase II promoter	P			IMP
positive regulation of tumor necrosis factor production	P	IEA	IMP IGI IMP
positive regulation of smooth muscle cell proliferation	P			IMP
interferon type I biosynthetic process	P	IEA	IMP	ISS
positive regulation of I-kappaB kinase/NF-kappaB cascade	P	IEP	IMP IGI	TAS
JNK cascade	P			IMP
positive regulation of tumor necrosis factor biosynthetic process	P	IEA		ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un
immune system phenotype	MP		Un Un
hematopoietic system phenotype	MP		Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Toll-like receptor signaling pathway (04620)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Apoptosis (04210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway