| IPI00793994 - IGF1, INSULIN-LIKE GROWTH FACTOR I PRECURSOR. | |
|---|---|
| Uniprot Accession: Q9NP10 | |
| Uniprot ID: Q9NP10_HUMAN | |
| Mapping: Chr 12, 101313809 - 101398471 | |
| Entrez Gene: 3479 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6895) |
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| Rat: Igf1, ISOFORM IGF-IA OF INSULIN-LIKE GROWTH FACTOR I PRECURSOR. |
| Mouse: Igf1, ISOFORM IGF-IA OF INSULIN-LIKE GROWTH FACTOR I PRECURSOR. |
| Mouse: Igf1, ISOFORM IGF-IB OF INSULIN-LIKE GROWTH FACTOR I PRECURSOR. |
| Mouse: Igf1, SEQUENCE. |
| Mouse: Igf1, INSULIN-LIKE GROWTH FACTOR 1 ISOFORM EB. |
| Rat: Igf1, 15 KDA PROTEIN. |
| Rat: Igf1, INSULIN-LIKE GROWTH FACTOR 1 ISOFORM C. |
| Rat: Igf1, INSULIN-LIKE GROWTH FACTOR 1 ISOFORM B. |
| Rat: Igf1, INSULIN-LIKE GROWTH FACTOR 1 ISOFORM A. |
| Human: IGF1, INSULIN-LIKE GROWTH FACTOR IA PRECURSOR. |
| Human: IGF1, INSULIN-LIKE GROWTH FACTOR IB PRECURSOR. |
| Human: IGF1, INSULIN-LIKE GROWTH FACTOR I PRECURSOR. |
| Human: IGF1, 3 KDA PROTEIN. |
| Human: IGF1, 15 KDA PROTEIN. |
| Human: IGF1, INSULIN-LIKE GROWTH FACTOR-I. |
| Human: IGF1, 18 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| interstitial matrix | C | IDA | ||
| extracellular space | C | IDA IDA | ISS | |
| extracellular region | C | NAS IEA | IEA | ISS IEA |
| insulin-like growth factor receptor binding | F | TAS | IPI | ISS ISS IDA |
| hormone activity | F | TAS IEA | IEA | ISS IDA IEA |
| steroid binding | F | IDA | ||
| growth factor activity | F | IEA | IEA | TAS |
| protein binding | F | IPI IPI | ISS IPI | |
| prothoracicotrophic hormone activity | F | IEA | IEA | IEA |
| female pregnancy | P | IEP | ||
| insulin-like growth factor receptor signaling pathway | P | IC IDA | ISS IDA | |
| positive regulation of anti-apoptosis | P | IDA | ||
| regulation of cell proliferation | P | IDA | ||
| mammary gland development | P | IMP | ||
| positive regulation of cell proliferation | P | TAS | ISS | |
| memory | P | IMP | ||
| regulation of steroid hormone receptor signaling pathway | P | IDA | ISS | |
| anti-apoptosis | P | IDA | ISS | |
| multicellular organism growth | P | IDA | ||
| nervous system development | P | IMP | ISS | |
| signal transduction | P | TAS | ISS | |
| positive regulation of calcium ion transport via voltage gated calcium channel | P | IDA | ||
| DNA replication | P | TAS | ISS | |
| water homeostasis | P | IGI | ||
| positive regulation of granule cell precursor proliferation | P | IDA | ||
| response to steroid hormone stimulus | P | IEP | ||
| organ morphogenesis | P | IMP | ISS | |
| positive regulation of cell growth | P | IDA IMP | ||
| muscle development | P | TAS | ISS | |
| cell motility | P | TAS | ISS | |
| branching morphogenesis of a tube | P | IMP | ||
| glial cell differentiation | P | IMP | ISS | |
| cell development | P | IMP | ISS | |
| positive regulation of osteoblast differentiation | P | IDA | ||
| Ras protein signal transduction | P | TAS | ISS | |
| regulation of protein metabolic process | P | IGI | ||
| positive regulation of fat cell differentiation | P | IDA | ||
| regulation of translation | P | IMP | ||
| response to mechanical stimulus | P | IEP | ||
| glycolate metabolic process | P | TAS | ISS | |
| skeletal development | P | TAS | ISS | |
| sensory perception of sound | P | IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| growth/size phenotype | MP | Un Un Un Un | ||
| other phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un Un Un | ||
| muscle phenotype | MP | Un Un | ||
| skeleton phenotype | MP | Un Un | ||
| hearing/vestibular/ear phenotype | MP | Un | ||
| nervous system phenotype | MP | Un Un | ||
| respiratory system phenotype | MP | Un Un | ||
| cardiovascular system phenotype | MP | Un | ||
| limbs/digits/tail phenotype | MP | Un | ||
| normal phenotype | MP | Un | ||
| lethality-postnatal | MP | Un | ||
| cardiac hypertrophy | N | IED |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Rheumatic Heart Disease | D | ISS | ||
| Cardiomyopathy, Hypertrophic | D | ISS | ||
| Carotid Artery Diseases | D | ISS | ||
| Growth Disorders | D | ISS | ||
| Myocardial Infarction | D | ISS | ||
| Cerebrovascular Accident | D | ISSIEP | ||
| Dementia, Vascular | D | ISS | ||
| Brain Ischemia | D | IED | ||
| Cardiomyopathy, Congestive | D | ISS | ||
| Myocardial Ischemia | D | ISSIED | ||
| Diabetic Retinopathy | D | ISS | ||
| Coronary Disease | D | ISS | ||
| Reperfusion Injury | D | ISS | ||
| Heart Failure, Congestive | D | IEP | ||
| Albuminuria | D | ISS | ||
| Hypertension | D | IAGP |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| phosphatidylinositol 3 kinase-Akt signaling pathway | W | ISSIMP | ||
| insulin-like growth factor signaling pathway | W | ISSIDA | ||
| p38 MAPK pathway | W | IMP | ||
| cardiovascular disease pathway | W | IEP | ||
| altered insulin-like growth factor signaling pathway | W | IEP |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glioma (05214) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Long-term depression (04730) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| mTOR signaling pathway (04150) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |