IpiRecord: IPI00794313

IPI00794313 - AKT2, 25 KDA PROTEIN.
Uniprot Accession: -NA-
Uniprot ID: -NA-
Mapping: Chr 19, 45430084 - 45483036
Entrez Gene: 208
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_575)
Rat: Akt2, RAC-BETA SERINE/THREONINE-PROTEIN KINASE.
Mouse: Akt2, RAC-BETA SERINE/THREONINE-PROTEIN KINASE.
Mouse: Akt2, 27 KDA PROTEIN.
Mouse: Akt2, 8 KDA PROTEIN.
Mouse: Akt2, 51 KDA PROTEIN.
Mouse: Akt2, 26 KDA PROTEIN.
Mouse: Akt2, 10 KDA PROTEIN.
Mouse: Akt2, 8 KDA PROTEIN.
Mouse: Akt2, 12 KDA PROTEIN.
Human: AKT2, RAC-BETA SERINE/THREONINE-PROTEIN KINASE.
Human: AKT2, AKT2 PROTEIN.
Human: AKT2, 23 KDA PROTEIN.
Human: AKT2, AKT2 PROTEIN.
Human: AKT2, 11 KDA PROTEIN.
Human: AKT2, 13 KDA PROTEIN.
Human: AKT2, 25 KDA PROTEIN.
Human: AKT2, 6 KDA PROTEIN.
Human: AKT2, 16 KDA PROTEIN.
Human: AKT2, 8 KDA PROTEIN.
Human: AKT2, 14 KDA PROTEIN.
Human: AKT2, PUTATIVE UNCHARACTERIZED PROTEIN (FRAGMENT).

Annotations for AKT2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytosolCIDA 
plasma membraneCIDA 
lamellipodiumCIDA ISS 
ATP bindingFIEA IEA IEA IEA 
protein bindingFIPI IPI ISS ISS IEA 
protein serine/threonine kinase activityFTAS IEA IEA IEA TAS ISS IDA IEA 
protein kinase activityFIEA 
nucleotide bindingFIEA IEA IEA 
kinase activityFIEA 
transferase activityFIEA IEA IEA 
protein modification processPTAS 
protein amino acid phosphorylationPIEA IEA TAS IDA IEA 
regulation of JNK cascadePIDA ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (16)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
cellular phenotypeMPUn
adipose tissue phenotypeMPUn Un
endocrine/exocrine gland phenotypeMPUn Un Un
homeostasis/metabolism phenotypeMPUn Un Un
growth/size phenotypeMPUn Un
lethality-embryonic/perinatalMPUn Un
skeleton phenotypeMPUn
reproductive system phenotypeMPUn
nervous system phenotypeMPUn
respiratory system phenotypeMPUn
digestive/alimentary phenotypeMPUn Un
muscle phenotypeMPUn Un
postnatal growth retardationNISS
increased circulating glucose levelNISS
increased circulating insulin levelNISS

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Insulin ResistanceDISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
phosphatidylinositol 3 kinase-Akt signaling pathwayWIMP

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
mTOR signaling pathway (04150)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Adipocytokine signaling pathway (04920)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Jak-STAT signaling pathway (04630)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Tight junction (04530)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Insulin signaling pathway (04910)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway