IpiRecord: IPI00108058

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
cytoplasm	C	IEA	IEA
nucleus	C	TAS IEA	IDA	ISS ISS IEA
cytosol	C	IEA	IDA
cyclin-dependent protein kinase holoenzyme complex	C	IEA	IPI	ISS
metal ion binding	F	IEA	IEA
cyclin binding	F	IEA	IPI	ISS
protein kinase inhibitor activity	F		IEA
protein kinase activity	F	NR		ISS
protein binding	F		IPI IPI IPI	ISS ISS
cyclin-dependent protein kinase inhibitor activity	F	TAS IEA	IDA	ISS ISS IEA
zinc ion binding	F	IEA	IEA
kinase activity	F	IEA	IEA	IEA
induction of apoptosis by intracellular signals	P	TAS		ISS
positive regulation of B cell proliferation	P	IEA	IGI	ISS
negative regulation of cyclin-dependent protein kinase activity	P	IEA	IDA	ISS
cell cycle arrest	P	TAS IEA	IDA	ISS ISS IEA
cell cycle	P	IEA	IEA
regulation of progression through cell cycle	P		IDA	ISS
negative regulation of cell proliferation	P	TAS	IMP IMP	ISS ISS
regulation of cyclin-dependent protein kinase activity	P			ISS
negative regulation of apoptosis	P	IEA	IMP	ISS
response to UV	P	IEA	IMP	ISS
positive regulation of non-apoptotic programmed cell death	P	IEA	IMP	ISS
response to DNA damage stimulus	P	IEA	IMP	ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (23)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un Un
craniofacial phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un Un
immune system phenotype	MP		Un Un
embryogenesis phenotype	MP		Un
lethality-embryonic/perinatal	MP		Un
skeleton phenotype	MP		Un
lethality-postnatal	MP		Un
muscle phenotype	MP		Un Un
renal/urinary system phenotype	MP		Un
respiratory system phenotype	MP		Un
vision/eye phenotype	MP		Un Un
tumorigenesis	MP		Un Un Un
normal phenotype	MP		Un
digestive/alimentary phenotype	MP		Un
limbs/digits/tail phenotype	MP		Un
reproductive system phenotype	MP		Un
hearing/vestibular/ear phenotype	MP		Un
hematopoietic system phenotype	MP		Un Un
growth/size phenotype	MP		Un Un
life span-post-weaning/aging	MP		Un
liver/biliary system phenotype	MP		Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Glioma (05214)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Chronic myeloid leukemia (05220)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cell cycle (04110)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway