IpiRecord: IPI00108982

IPI00108982 - Ciita, ISOFORM 1 OF MHC CLASS II TRANSACTIVATOR.
Uniprot Accession: Q3UNW8
Uniprot ID: Q3UNW8_MOUSE
Mapping: Chr 16, 10393637 - 10441141
Entrez Gene: 12265
Entrez MapView: Geneprod
MGI: MGI:108445
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_9062)
Rat: C2ta, MHC CLASS II TRANSACTIVATOR TYPE I.
Mouse: Ciita, ISOFORM 1 OF MHC CLASS II TRANSACTIVATOR.
Mouse: Ciita, ISOFORM 2 OF MHC CLASS II TRANSACTIVATOR.
Mouse: Ciita, CLONE:A430106F04 PRODUCT:HYPOTHETICAL PROTEIN, FULL INSERT SEQUENCE.
Mouse: Ciita, C2TA PROTEIN.
Mouse: Ciita, ISOFORM 3 OF MHC CLASS II TRANSACTIVATOR.
Rat: C2ta, MHC CLASS II TRANSACTIVATOR TYPE IV.
Human: CIITA, MHC CLASS II TRANSACTIVATOR.
Human: CIITA, MHC CLASS II TRANSACTIVATOR TYPE I (FRAGMENT).
Human: CIITA, MHC CLASS II TRANSACTIVATOR CIITAMED.
Human: CIITA, MHC CLASS II TRANSACTIVATOR CIITA.
Human: CIITA, CLASS II, MAJOR HISTOCOMPATIBILITY COMPLEX, TRANSACTIVATOR.
Human: CIITA, MHC CLASS II TRANSACTIVATOR CIITALO.
Human: CIITA, 126 KDA PROTEIN.

Annotations for Ciita and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
nucleusCIEA IC IC ISS 
RNA polymerase II transcription factor activityFTAS ISS 
nucleotide bindingFIEA IEA IEA 
transcription activator activityFIDA 
protein bindingFIEA IEA IEA 
DNA bindingFTAS 
transcription regulator activityFIEA IEA 
ATP bindingFIEA IEA IEA IEA 
transcription coactivator activityFTAS ISS 
ubiquitin bindingFIPI ISS 
transcription repressor activityFIMP IDA ISS 
defense responsePIEA 
negative regulation of transcription, DNA-dependentPIDA 
inflammatory responsePIEP 
positive regulation of MHC class II biosynthetic processPIDA IEP 
regulation of transcriptionPIEA IEA 
immune responsePTAS ISS 
positive regulation of transcription, DNA-dependentPIDA 
negative regulation of transcriptionPIMP ISS 
regulation of transcription, DNA-dependentPIEA IEA 
detection of biotic stimulusPISS 
transcriptionPIEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (6)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
endocrine/exocrine gland phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn Un Un Un Un
digestive/alimentary phenotypeMPUn
normal phenotypeMPUn
hematopoietic system phenotypeMPUn Un Un

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Severe Combined ImmunodeficiencyDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Antigen processing and presentation (04612)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway