| IPI00109561 - Ccnd1, G1/S-SPECIFIC CYCLIN-D1. | |
|---|---|
| Uniprot Accession: Q9QXH2 | |
| Uniprot ID: Q9QXH2_MOUSE | |
| Mapping: Chr 7, 144739321 - 144749220 | |
| Entrez Gene: 12443 | |
| Entrez MapView: |
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| MGI: MGI:88313 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1468) |
|---|
| Rat: Ccnd1, G1/S-SPECIFIC CYCLIN-D1. |
| Mouse: Ccnd1, G1/S-SPECIFIC CYCLIN-D1. |
| Human: CCND1, G1/S-SPECIFIC CYCLIN-D1. |
| Human: CCND1, CYCLIN D1 (FRAGMENT). |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular_component | C | ND | ||
| cytosol | C | IEA | IDA | ISS IEA |
| cyclin-dependent protein kinase holoenzyme complex | C | IEA | IPI | ISS IEA |
| nucleus | C | IEA | IDA | ISS IEA |
| intracellular | C | IDA | IEA | |
| protein binding | F | IPI IPI IPI IPI | IPI IPI | ISS ISS IEA |
| cyclin-dependent protein kinase regulator activity | F | IEA | IDA | ISS IEA |
| kinase activity | F | IDA | ISS | |
| protein kinase binding | F | IDA | ||
| protein kinase activity | F | IEA | IDA | ISS IEA |
| G1/S transition of mitotic cell cycle | P | NAS | ISS | |
| regulation of progression through cell cycle | P | IDA IDA | TAS ISS TAS | |
| fat cell differentiation | P | IEA | IDA | ISS IEA |
| protein amino acid phosphorylation | P | IEA | IDA IDA | ISS IEA |
| cell cycle | P | IEA | IDA | IEA |
| unfolded protein response | P | IEA | IDA | IEA |
| response to calcium ion | P | IEP | ||
| cell division | P | IEA | IEA | IEA |
| response to iron ion | P | IEP | ||
| re-entry into mitotic cell cycle | P | IEA | IDA | ISS IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un | ||
| craniofacial phenotype | MP | Un | ||
| growth/size phenotype | MP | Un Un Un Un | ||
| endocrine/exocrine gland phenotype | MP | Un Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| behavior/neurological phenotype | MP | Un Un Un Un | ||
| life span-post-weaning/aging | MP | Un | ||
| immune system phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un Un | ||
| skeleton phenotype | MP | Un | ||
| lethality-postnatal | MP | Un Un | ||
| cardiovascular system phenotype | MP | Un | ||
| reproductive system phenotype | MP | Un Un Un Un | ||
| hematopoietic system phenotype | MP | Un | ||
| respiratory system phenotype | MP | Un | ||
| vision/eye phenotype | MP | Un Un Un Un | ||
| nervous system phenotype | MP | Un Un | ||
| tumorigenesis | N | Un Un Un | ISS | |
| increased cell proliferation | N | IED | ||
| Increased Cell Size | N | IED | ||
| decreased body size | N | ISS | ||
| cardiac hypertrophy | N | IED | ||
| abnormal liver regeneration | N | IED |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Cardiomegaly | D | IED | ||
| Multiple Myeloma | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| S phase | W | IEA | ||
| G1 phase | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glioma (05214) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Chronic myeloid leukemia (05220) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cell cycle (04110) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Jak-STAT signaling pathway (04630) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Wnt signaling pathway (04310) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Colorectal cancer (05210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pancreatic cancer (05212) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |