IpiRecord: IPI00110556

IPI00110556 - Cyp2e1, CYTOCHROME P450 2E1.
Uniprot Accession: Q05421
Uniprot ID: CP2E1_MOUSE
Mapping: Chr 7, 140615152 - 140626301
Entrez Gene: 13106
Entrez MapView: Geneprod
MGI: MGI:88607
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1344)
Rat: Cyp2e1, CYTOCHROME P450 2E1.
Mouse: Cyp2e1, CYTOCHROME P450 2E1.
Mouse: Cyp2e1, CYTOCHROME P450 2E1.
Mouse: Cyp2e1, CYTOCHROME P450 2E1.
Human: CYP2E1, CYTOCHROME P450 2E1.
Human: CYP2E1, (FRAGMENT).
Human: CYP2E1, CYTOCHROME P450 2E1 (FRAGMENT).
Human: CYP2E1, CYTOCHROME P450 2E1 (FRAGMENT).

Annotations for Cyp2e1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
endoplasmic reticulumCIEA IEA IEA 
extracellular spaceCRCA ISS 
membraneCIEA IEA IEA 
microsomeCIEA IDA IDA ISS IEA 
monooxygenase activityFIEA IDA ISS TAS ISS 
iron ion bindingFIEA IEA IEA IEA 
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygenFIEA 
metal ion bindingFIEA IEA IEA 
heme bindingFIEA IEA IEA 
oxygen bindingFTAS ISS 
unspecific monooxygenase activityFIEA IEA 
oxidoreductase activityFIEA 
xenobiotic metabolic processPNAS 
electron transportPIEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (1)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
ObesityDIEP
Obesity, MorbidDISS
Fatty LiverDISS

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
fatty acid metabolic pathwayWIEA
gamma-hexachlorocyclohexane degradation pathwayWIEA
tryptophan metabolic pathwayWIEA

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Metabolism of xenobiotics by cytochrome P450 (00980)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Arachidonic acid metabolism (00590)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Linoleic acid metabolism (00591)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway