IPI report for IPI00111807

IpiRecord: IPI00111807

IPI00111807 - F8, COAGULATION FACTOR VIII PRECURSOR.
Uniprot Accession: Q8BQ43
Uniprot ID: Q8BQ43_MOUSE
Mapping: Chr X, 71425575 - 71635036
Entrez Gene: 14069
Entrez MapView:
MGI: MGI:88383
+All IPI Database Cross References UniProtKB/Swiss-Prot: Q06194 UniProtKB/Swiss-Prot: FA8_MOUSE Vega: OTTMUSP00000022815 UniProtKB/TrEMBL: A2AHV1 UniProtKB/TrEMBL: A2AHV1_MOUSE UniProtKB/TrEMBL: Q684Q7 UniProtKB/TrEMBL: Q684Q7_MOUSE UniProtKB/TrEMBL: Q8BQ43 UniProtKB/TrEMBL: Q8BQ43_MOUSE ENSEMBL: ENSMUSP00000033539 ENSEMBL: ENSMUSG00000031196 REFSEQ_PROVISIONAL: NP_032003 REFSEQ_PROVISIONAL: GI:6679733 UniParc: UPI00000275E4 MGI: MGI:88383 Entrez Gene: 14069 UniGene: Mm.1805 CCDS: CCDS30238.1 trome: MTR041291 RZPD: Mm.1805 CleanEx: MM_F8 InterPro: IPR000421 InterPro: IPR001117 InterPro: IPR011706 InterPro: IPR011707 InterPro: IPR002355 InterPro: IPR008972 InterPro: IPR014707 InterPro: IPR008979 Pfam: PF00394 Pfam: PF07731 Pfam: PF07732 Pfam: PF00754 SMART: SM00231 PROSITE: PS01285 PROSITE: PS01286 PROSITE: PS50022 PROSITE: PS00079 SUPERFAMILY: SSF49503 SUPERFAMILY: SSF49785 PANTHER: PTHR10127:SF50 GENE3D: G3DSA:2.60.40.420

IPI00111807 - F8, COAGULATION FACTOR VIII PRECURSOR.

Uniprot Accession: Q8BQ43

Uniprot ID: Q8BQ43_MOUSE

Mapping: Chr X, 71425575 - 71635036

Entrez Gene: 14069

Entrez MapView: Geneprod

MGI: MGI:88383

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13429)
Rat: F8, FACTOR VIII.
Mouse: F8, COAGULATION FACTOR VIII PRECURSOR.
Mouse: F8, COAGULATION FACTOR VIII.
Human: F8, COAGULATION FACTOR VIII ISOFORM B PRECURSOR.
Human: F8, COAGULATION FACTOR VIII PRECURSOR.
Human: F8, COAGULATION FACTOR VIII, PROCOAGULANT COMPONENT.
Human: F8, COAGULATION FACTOR VIII, PROCOAGULANT COMPONENT.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13429)

Rat: F8, FACTOR VIII.

Mouse: F8, COAGULATION FACTOR VIII PRECURSOR.

Mouse: F8, COAGULATION FACTOR VIII.

Human: F8, COAGULATION FACTOR VIII ISOFORM B PRECURSOR.

Human: F8, COAGULATION FACTOR VIII PRECURSOR.

Human: F8, COAGULATION FACTOR VIII, PROCOAGULANT COMPONENT.

Annotations for F8 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
extracellular space	C		RCA	ISS IDA
extracellular region	C	NAS
calcium ion binding	F	IEA	IEA	IEA
metal ion binding	F		IEA
protein binding	F	IPI
copper ion binding	F	IEA	IEA	IEA
oxidoreductase activity	F	IEA	IEA	IEA
acute-phase response	P	IEA	IEA
cell adhesion	P	IEA	IEA	IEA
blood coagulation, intrinsic pathway	P			IMP
blood coagulation	P	TAS	IEA IEA	IEA ISS

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
homeostasis/metabolism phenotype	MP		Un
normal phenotype	MP		Un

Disease (4)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Rat
Hemophilia A	D	ISS
Venous Thrombosis	D	ISS
Cerebrovascular Accident	D	ISS
Thromboembolism	D	ISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
coagulation cascade pathway	W			IMP

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Complement and coagulation cascades (04610)	Present in KEGG pathway	Present in KEGG pathway	Not present in KEGG pathway