IpiRecord: IPI00114206

IPI00114206 - F2, PROTHROMBIN PRECURSOR (FRAGMENT).
Uniprot Accession: Q3TJ94
Uniprot ID: Q3TJ94_MOUSE
Mapping: Chr 2, 91426157 - 91437253
Entrez Gene: 14061
Entrez MapView: Geneprod
MGI: MGI:88380
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_3370)
Rat: F2, PROTHROMBIN PRECURSOR (FRAGMENT).
Mouse: F2, PROTHROMBIN PRECURSOR (FRAGMENT).
Human: F2, PROTHROMBIN PRECURSOR (FRAGMENT).
Human: F2, 70 KDA PROTEIN.
Human: F2, PROTHROMBIN B-CHAIN.
Human: F2, PROTHROMBIN (FRAGMENT).

Annotations for F2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular regionCNAS IEA IEA IEA IDA 
soluble fractionCTAS 
extracellular spaceCTAS RCA ISS 
receptor bindingFIPI IEA 
peptidase activityFIEA IEA IEA 
protein domain specific bindingFISS 
hydrolase activityFIEA 
thrombin activityFIDA IEA IEA IEA TAS IDA IEA 
catalytic activityFIEA 
calcium ion bindingFIEA IEA IEA IEA 
serine-type endopeptidase activityFIEA IEA 
platelet activationPTAS IDA 
regulation of progression through cell cyclePTAS 
STAT protein nuclear translocationPTAS 
response to woundingPTAS 
apoptosisPTAS 
fibrinolysisPIDA IEA 
regulation of blood coagulationPTAS 
tyrosine phosphorylation of STAT proteinPTAS 
acute-phase responsePIEA IEA IEA 
response to stressPIEP 
wound healingPTAS 
caspase activationPTAS 
proteolysisPTAS IEA IEA TAS IEA 
multicellular organismal developmentPTAS 
blood coagulationPIEA IEA IEA IEA TAS IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (3)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn Un
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn Un

Disease (5)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
GlioblastomaDISS
HypoprothrombinemiasDISS
Venous ThrombosisDISS
GliomaDIED
ThromboembolismDISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
protein C anticoagulant pathwayWISS
coagulation cascade pathwayWTAS

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Neuroactive ligand-receptor interaction (04080)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Complement and coagulation cascades (04610)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway