| IPI00114206 - F2, PROTHROMBIN PRECURSOR (FRAGMENT). | |
|---|---|
| Uniprot Accession: Q3TJ94 | |
| Uniprot ID: Q3TJ94_MOUSE | |
| Mapping: Chr 2, 91426157 - 91437253 | |
| Entrez Gene: 14061 | |
| Entrez MapView: |
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| MGI: MGI:88380 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_3370) |
|---|
| Rat: F2, PROTHROMBIN PRECURSOR (FRAGMENT). |
| Mouse: F2, PROTHROMBIN PRECURSOR (FRAGMENT). |
| Human: F2, PROTHROMBIN PRECURSOR (FRAGMENT). |
| Human: F2, 70 KDA PROTEIN. |
| Human: F2, PROTHROMBIN B-CHAIN. |
| Human: F2, PROTHROMBIN (FRAGMENT). |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| extracellular region | C | NAS IEA | IEA | IEA IDA |
| soluble fraction | C | TAS | ||
| extracellular space | C | TAS | RCA | ISS |
| receptor binding | F | IPI | IEA | |
| peptidase activity | F | IEA | IEA | IEA |
| protein domain specific binding | F | ISS | ||
| hydrolase activity | F | IEA | ||
| thrombin activity | F | IDA IEA | IEA IEA | TAS IDA IEA |
| catalytic activity | F | IEA | ||
| calcium ion binding | F | IEA | IEA IEA | IEA |
| serine-type endopeptidase activity | F | IEA IEA | ||
| platelet activation | P | TAS | IDA | |
| regulation of progression through cell cycle | P | TAS | ||
| STAT protein nuclear translocation | P | TAS | ||
| response to wounding | P | TAS | ||
| apoptosis | P | TAS | ||
| fibrinolysis | P | IDA | IEA | |
| regulation of blood coagulation | P | TAS | ||
| tyrosine phosphorylation of STAT protein | P | TAS | ||
| acute-phase response | P | IEA | IEA | IEA |
| response to stress | P | IEP | ||
| wound healing | P | TAS | ||
| caspase activation | P | TAS | ||
| proteolysis | P | TAS IEA | IEA | TAS IEA |
| multicellular organismal development | P | TAS | ||
| blood coagulation | P | IEA | IEA IEA IEA | TAS IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| homeostasis/metabolism phenotype | MP | Un Un | ||
| embryogenesis phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Glioblastoma | D | ISS | ||
| Hypoprothrombinemias | D | ISS | ||
| Venous Thrombosis | D | ISS | ||
| Glioma | D | IED | ||
| Thromboembolism | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| protein C anticoagulant pathway | W | ISS | ||
| coagulation cascade pathway | W | TAS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Neuroactive ligand-receptor interaction (04080) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Complement and coagulation cascades (04610) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |