IpiRecord: IPI00115051

IPI00115051 - Pdgfa, PLATELET DERIVED GROWTH FACTOR, ALPHA.
Uniprot Accession: Q9CU96
Uniprot ID: Q9CU96_MOUSE
Mapping: Chr 5, 139229656 - 139248584
Entrez Gene: 18590
Entrez MapView: Geneprod
MGI: MGI:97527
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10869)
Rat: Pdgfa, ISOFORM LONG OF PLATELET-DERIVED GROWTH FACTOR A CHAIN PRECURSOR.
Mouse: Pdgfa, PLATELET DERIVED GROWTH FACTOR, ALPHA.
Mouse: Pdgfa, ISOFORM LONG OF PLATELET-DERIVED GROWTH FACTOR A CHAIN PRECURSOR.
Mouse: Pdgfa, PLATELET-DERIVED GROWTH FACTOR ALPHA.
Rat: Pdgfa, PDGFA PROTEIN.
Rat: Pdgfa, 21 KDA PROTEIN.
Human: PDGFA, ISOFORM LONG OF PLATELET-DERIVED GROWTH FACTOR A CHAIN PRECURSOR.
Human: PDGFA, ISOFORM SHORT OF PLATELET-DERIVED GROWTH FACTOR A CHAIN PRECURSOR.
Human: PDGFA, PLATELET-DERIVED GROWTH FACTOR ALPHA POLYPEPTIDE.
Human: PDGFA, PLATELET-DERIVED GROWTH FACTOR A-CHAIN (FRAGMENT).

Annotations for Pdgfa and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
microvillusCIDA ISS 
extracellular spaceCRCA ISS ISS 
membraneCIEA IEA IEA 
platelet-derived growth factor receptor bindingFISS 
growth factor activityFIEA IEA IEA TAS IEA 
cell proliferationPIEA IEA ISS IEA 
regulation of progression through cell cyclePIEA IEA IEA 
regulation of peptidyl-tyrosine phosphorylationPIDA ISS 
actin cytoskeleton organization and biogenesisPIDA ISS 
response to hypoxiaPIEP 
transforming growth factor beta receptor signaling pathwayPIEP 
cell-cell signalingPISS 
cell projection biogenesisPIDA ISS 
cell surface receptor linked signal transductionPISS 
positive regulation of cell proliferationPISS ISS 
angiogenesisPIDA ISS 
alveolus developmentPIMP ISS 
organ morphogenesisPIMP IGI ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (14)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
craniofacial phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn
skeleton phenotypeMPUn
lethality-postnatalMPUn
muscle phenotypeMPUn
renal/urinary system phenotypeMPUn
nervous system phenotypeMPUn
respiratory system phenotypeMPUn
cardiovascular system phenotypeMPUn
reproductive system phenotypeMPUn
growth/size phenotypeMPUn

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Hypertension, PulmonaryDIEP

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (6)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Not present in KEGG pathwayPresent in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway