IpiRecord: IPI00115157

IPI00115157 - Snca, ISOFORM 1 OF ALPHA-SYNUCLEIN.
Uniprot Accession: O55042-1
Uniprot ID: SYUA_MOUSE
Mapping: Chr 6, 60661224 - 60759433
Entrez Gene: 20617
Entrez MapView: Geneprod
MGI: MGI:1277151
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4631)
Rat: Snca, ISOFORM SYN1 OF ALPHA-SYNUCLEIN.
Mouse: Snca, ISOFORM 1 OF ALPHA-SYNUCLEIN.
Mouse: Snca, ISOFORM 2 OF ALPHA-SYNUCLEIN.
Rat: Snca, ISOFORM SYN2 OF ALPHA-SYNUCLEIN.
Rat: Snca, ISOFORM SYN3 OF ALPHA-SYNUCLEIN.
Human: SNCA, ISOFORM 1 OF ALPHA-SYNUCLEIN.
Human: SNCA, ISOFORM 2-4 OF ALPHA-SYNUCLEIN.
Human: SNCA, ISOFORM 2-5 OF ALPHA-SYNUCLEIN.

Annotations for Snca and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
synaptosomeCIDA ISS 
cytoplasmCIEA IEA IDA ISS 
protein N-terminus bindingFIPI 
protein bindingFISS 
identical protein bindingFIDA ISS 
synaptic transmission, dopaminergicPIMP IMP ISS 
regulation of long-term neuronal synaptic plasticityPIMP ISS 
phospholipid metabolic processPIMP ISS 
regulation of locomotionPIMP ISS 
regulation of neurotransmitter secretionPIMP IMP IMP ISS 
dopamine metabolic processPIGI ISS 
dopamine biosynthetic processPIMP ISS 
central nervous system developmentPISS 
anti-apoptosisPISS 
positive regulation of neurotransmitter secretionPIDA ISS 
response to drugPIMP ISS 
synaptic vesicle transportPIMP ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (5)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
nervous system phenotypeMP##
decreased dopamine levelNISS
abnormal locomotor activityNISS
alcohol preferenceNISS
hypoactivityNISS

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (4)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
Parkinson disease pathwayWIEA IDA
altered ubiquitin/proteasome degradation pathwayWISS
ubiquitin/proteasome degradation pathwayWISS
Alzheimer disease pathwayWIEA ISS

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Alzheimer's disease (05010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Parkinson's disease (05020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Neurodegenerative Disorders (01510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway