IpiRecord: IPI00115599

IPI00115599 - Hsd11b1, CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1.
Uniprot Accession: Q4JHD9
Uniprot ID: Q4JHD9_MOUSE
Mapping: Chr 1, 194922413 - 194964769
Entrez Gene: 15483
Entrez MapView: Geneprod
MGI: MGI:103562
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11628)
Rat: Hsd11b1, ISOFORM 11-HSD1A OF CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1.
Mouse: Hsd11b1, CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1.
Rat: Hsd11b1, LRRGT00065.
Rat: Hsd11b1, ISOFORM 11-HSD1B OF CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1.
Human: HSD11B1, CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1.

Annotations for Hsd11b1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
rough endoplasmic reticulumCIDA 
integral to membraneCIEA IEA 
nuclear membraneCIDA 
membraneCIEA IEA 
microsomeCIEA IEA IDA 
apical part of cellCIDA 
cytoplasmCIDA 
endoplasmic reticulumCIEA IEA 
11-beta-hydroxysteroid dehydrogenase activityFIDA IMP IDA ISS IMP 
NADP bindingFIDA 
steroid bindingFIPI 
oxidoreductase activityFIEA IEA IEA IDA 
RNA bindingFIEA 
11-beta-hydroxysteroid dehydrogenase (NADP+) activityFIEA IEA 
RNA-directed DNA polymerase activityFIEA 
metabolic processPIEA IEA IDA 
lung developmentPIEA IMP ISS 
blood pressure regulationPISS 
lipid metabolic processPIEA IEA 
RNA-dependent DNA replicationPIEA 
steroid metabolic processPIEA IEA 
regulation of pentose-phosphate shuntPIDA 
glucocorticoid biosynthetic processPIDA 
glucocorticoid catabolic processPIDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (6)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
adipose tissue phenotypeMP#
behavior/neurological phenotypeMP#
endocrine/exocrine gland phenotypeMP#
homeostasis/metabolism phenotypeMP#
nervous system phenotypeMP#
respiratory system phenotypeMP#

Disease (5)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Metabolism, Inborn ErrorsDISS
ObesityDISSIED
Metabolic Syndrome XDIEP
Diabetes Mellitus, Non-Insulin-DependentDIEP
HyperlipidemiaDIEP

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
C21-Steroid hormone metabolic pathwayWIEA
androgen and estrogen metabolic pathwayWIEA

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
C21-Steroid hormone metabolism (00140)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Androgen and estrogen metabolism (00150)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway