IpiRecord: IPI00116121

IPI00116121 - Bace1, BETA-SECRETASE 1 PRECURSOR.
Uniprot Accession: Q9CUU5
Uniprot ID: Q9CUU5_MOUSE
Mapping: Chr 9, 45589575 - 45613479
Entrez Gene: 23821
Entrez MapView: Geneprod
MGI: MGI:1346542
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7823)
Rat: Bace1, BETA-SECRETASE 1 PRECURSOR.
Mouse: Bace1, BETA-SECRETASE 1 PRECURSOR.
Mouse: Bace1, SEQUENCE.
Rat: Bace1, 56 KDA PROTEIN.
Rat: Bace1, 56 KDA PROTEIN.
Rat: Bace1, 44 KDA PROTEIN.
Human: BACE1, ISOFORM A OF BETA-SECRETASE 1 PRECURSOR.
Human: BACE1, ISOFORM B OF BETA-SECRETASE 1 PRECURSOR.
Human: BACE1, ISOFORM C OF BETA-SECRETASE 1 PRECURSOR.
Human: BACE1, ISOFORM D OF BETA-SECRETASE 1 PRECURSOR.
Human: BACE1, PUTATIVE UNCHARACTERIZED PROTEIN DKFZP564D083.
Human: BACE1, HSPC104.
Human: BACE1, KIAA1149 PROTEIN (FRAGMENT).

Annotations for Bace1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
endosomeCISS ISS IDA 
membraneCIEA IEA 
cytoplasmic vesicleCIDA ISS 
axonCIDA ISS 
integral to membraneCRCA IEA ISS 
Golgi apparatusCISS ISS IDA 
pepsin A activityFIEA IEA IEA 
aspartic-type endopeptidase activityFIEA IEA 
aspartic-type signal peptidase activityFIEA IEA IEA 
hydrolase activityFIEA 
peptidase activityFIEA IEA IDA 
endopeptidase activityFIDA ISS 
proteolysisPIEA IDA IEA ISS 
beta-amyloid metabolic processPISS ISS IMP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn
behavior/neurological phenotypeMPUn Un
lethality-postnatalMPUn
muscle phenotypeMPUn
nervous system phenotypeMPUn
normal phenotypeMPUn Un Un
growth/size phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
Alzheimer disease pathwayWIEA

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Alzheimer's disease (05010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway