| IPI00117779 - Bdkrb1, B1 BRADYKININ RECEPTOR. | |
|---|---|
| Uniprot Accession: Q0VBD7 | |
| Uniprot ID: Q0VBD7_MOUSE | |
| Mapping: Chr 12, 106005141 - 106006478 | |
| Entrez Gene: 12061 | |
| Entrez MapView: |
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| MGI: MGI:88144 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6533) |
|---|
| Rat: Bdkrb1, B1 BRADYKININ RECEPTOR. |
| Mouse: Bdkrb1, B1 BRADYKININ RECEPTOR. |
| Human: BDKRB1, B1 BRADYKININ RECEPTOR. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| integral to plasma membrane | C | TAS | ||
| plasma membrane | C | TAS TAS | IDA | |
| membrane fraction | C | IDA | ||
| neuron projection | C | IDA | ||
| integral to membrane | C | RCA | ISS IEA | |
| endoplasmic reticulum | C | TAS | ||
| membrane | C | IEA | IEA | |
| peptide binding | F | IPI | ||
| signal transducer activity | F | IEA | ||
| bradykinin receptor activity | F | TAS | RCA | IDA ISS IEA |
| G-protein coupled receptor activity | F | IEA | ||
| rhodopsin-like receptor activity | F | IEA | IEA | IEA |
| receptor activity | F | IEA | IEA | IEA |
| protein kinase C activation | P | IDA | ||
| signal transduction | P | IEA | IEA | IEA |
| inflammatory response | P | NR | IMP | |
| elevation of cytosolic calcium ion concentration | P | TAS | ||
| negative regulation of cell growth | P | IMP | ||
| positive regulation of release of sequestered calcium ion into cytosol | P | IDA IDA | ||
| negative regulation of blood pressure | P | IMP | ||
| sensory perception of pain | P | IMP | ||
| positive regulation of leukocyte migration | P | IMP | ||
| negative regulation of protein amino acid phosphorylation | P | IMP | ||
| G-protein coupled receptor protein signaling pathway | P | IEA | IEA IEA | TAS IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| homeostasis/metabolism phenotype | MP | Un | ||
| behavior/neurological phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| life span-post-weaning/aging | MP | Un | ||
| cardiovascular system phenotype | MP | Un | ||
| renal/urinary system phenotype | MP | Un | ||
| normal phenotype | MP | Un | ||
| touch/vibrissae phenotype | MP | Un | ||
| renal fibrosis | N | IED | ||
| resistance to induced joint inflammation | N | IED | ||
| hyperalgesia | N | IED | ||
| increased blood pressure | N | IEDIED | ||
| extremity edema | N | IED | ||
| albuminuria | N | IED | ||
| abnormal inflammatory response | N | ISS | ||
| impaired wound healing | N | IED |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Hyperalgesia | D | IED | ||
| Obesity | D | ISS | ||
| Hypertension | D | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Neuroactive ligand-receptor interaction (04080) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Calcium signaling pathway (04020) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Complement and coagulation cascades (04610) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |