| IPI00118239 - Srd5a2, 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2. | |
|---|---|
| Uniprot Accession: Q99NA0 | |
| Uniprot ID: Q99NA0_MOUSE | |
| Mapping: Chr 17, 73922606 - 73952814 | |
| Entrez Gene: 94224 | |
| Entrez MapView: |
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| MGI: MGI:2150380 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6168) |
|---|
| Rat: Srd5a2, 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2. |
| Mouse: Srd5a2, 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2. |
| Human: SRD5A2, 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular_component | C | ND | ||
| membrane | C | IEA | RCA | ISS IEA |
| integral to membrane | C | IEA | RCA | ISS IEA |
| microsome | C | IEA | IEA | IEA |
| endoplasmic reticulum | C | IEA | IEA | IEA |
| 3-oxo-5-alpha-steroid 4-dehydrogenase activity | F | IEA | IMP IMP | IDA ISS IEA |
| oxidoreductase activity | F | IEA | IEA | IEA |
| sterol 5-alpha reductase activity | F | IDA | ISS IEA | |
| male genitalia development | P | IEA | IMP | TAS ISS IEA |
| response to steroid hormone stimulus | P | IEP | ||
| androgen biosynthetic process | P | IEA | IMP | ISS IEA |
| response to peptide hormone stimulus | P | IDA | ||
| response to organic substance | P | IDA | ||
| cell differentiation | P | IEA | IEA | IEA |
| cell-cell signaling | P | TAS | ISS | |
| steroid catabolic process | P | IDA | ||
| sex determination | P | IEA | ||
| sex differentiation | P | IEA | IEA | TAS IEA |
| androgen metabolic process | P | ISS | ||
| steroid biosynthetic process | P | IMP | IDA ISS | |
| response to drug | P | IDA | ||
| male gonad development | P | IMP | ISS IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| endocrine/exocrine gland phenotype | MP | Un | ||
| reproductive system phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Diabetes Mellitus | D | IEP | ||
| Hypospadias | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| bile acid biosynthetic pathway | W | IEA | ||
| androgen and estrogen metabolic pathway | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Androgen and estrogen metabolism (00150) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Bile acid biosynthesis (00120) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |