IpiRecord: IPI00121080

IPI00121080 - Map3k7, MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7.
Uniprot Accession: Q543B5
Uniprot ID: Q543B5_MOUSE
Mapping: Chr 4, 32292729 - 32349408
Entrez Gene: 26409
Entrez MapView: Geneprod
MGI: MGI:1346877
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5284)
Rat: Map3k7_predicted, 64 KDA PROTEIN.
Mouse: Map3k7, MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7.
Mouse: Map3k7, MAP3K7 PROTEIN.
Mouse: Map3k7, MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 7.
Mouse: Map3k7, MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 7.
Rat: Map3k7_predicted, SIMILAR TO MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7.
Rat: Map3k7_predicted, SIMILAR TO MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7.
Human: MAP3K7, ISOFORM 1A OF MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7.
Human: MAP3K7, ISOFORM 1C OF MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7.
Human: MAP3K7, MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 ISOFORM D.
Human: MAP3K7, ISOFORM 1B OF MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7.
Human: MAP3K7, PUTATIVE UNCHARACTERIZED PROTEIN DKFZP586F0420.

Annotations for Map3k7 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
kinase activityFIEA IEA 
nucleotide bindingFIEA IEA 
protein bindingFIPI ISS IPI 
MAP kinase kinase kinase activityFRCA ISS 
protein-tyrosine kinase activityFIEA RCA ISS IEA 
ATP bindingFIEA IEA IEA IEA 
protein serine/threonine kinase activityFIEA IEA IEA IEA 
magnesium ion bindingFIEA 
metal ion bindingFIEA 
transferase activityFIEA IEA 
protein kinase activityFIEA 
MAP kinase kinase activityFIDA 
protein amino acid phosphorylationPIEA IDA IEA 
MAPKKK cascadePIDA ISS 
angiogenesisPIMP ISS 
neural tube formationPIMP ISS 
transforming growth factor beta receptor signaling pathwayPRCA IMP ISS 
positive regulation of I-kappaB kinase/NF-kappaB cascadePIGI ISS 
negative regulation of apoptosisPIGI IMP ISS 
positive regulation of JNK cascadePIGI ISS 
I-kappaB phosphorylationPIGI ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (13)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn Un Un
craniofacial phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn Un
embryogenesis phenotypeMPUn Un
lethality-embryonic/perinatalMPUn Un Un
muscle phenotypeMPUn
nervous system phenotypeMPUn
digestive/alimentary phenotypeMPUn
cardiovascular system phenotypeMPUn Un
limbs/digits/tail phenotypeMPUn
hematopoietic system phenotypeMPUn Un
growth/size phenotypeMPUn Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Adherens junction (04520)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway