IpiRecord: IPI00121842

IPI00121842 - Tap2, TAP2.
Uniprot Accession: Q80WF7
Uniprot ID: Q80WF7_MOUSE
Mapping: Chr 17, 33814426 - 33826594
Entrez Gene: 21355
Entrez MapView: Geneprod
MGI: MGI:98484
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14416)
Rat: Tap2, ANTIGEN PEPTIDE TRANSPORTER 2.
Mouse: Tap2, TAP2.
Human: TAP2, TRANSPORTER 2, ATP-BINDING CASSETTE, SUB-FAMILY B ISOFORM 2.
Human: TAP2, ANTIGEN PEPTIDE TRANSPORTER 2.
Human: TAP2, TAP2 PROTEIN (FRAGMENT).

Annotations for Tap2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to plasma membraneCIEA 
extracellular spaceCRCA ISS 
TAP complexCNAS 
cytosolCNAS 
membraneCIEA IEA IEA 
integral to membraneCIEA NAS RCA ISS IEA 
endoplasmic reticulumCIEA IEA IEA 
MHC class I peptide loading complexCIDA 
endoplasmic reticulum lumenCISS IMP IEA 
phosphate bindingFNAS 
transporter activityFIEA IDA IEA IEA 
nucleotide bindingFIEA IEA IEA IDA IEA 
peptide bindingFIDA 
peptide antigen-transporting ATPase activityFNAS TAS 
ATP bindingFIEA NAS IEA IEA IMP IEA 
MHC class I protein bindingFNAS IDA 
ATPase activity, coupled to transmembrane movement of substancesFIEA IEA IEA 
oligopeptide transporter activityFIEA IEA IEA 
tapasin bindingFISS IPI IEA 
homoaconitate hydratase activityFNAS 
nucleoside-triphosphatase activityFIEA 
ATPase activityFIEA IEA IEA 
TAP2 bindingFIPI 
protein heterodimerization activityFISS IPI IEA 
TAP1 bindingFIPI 
protein bindingFIPI ISS 
protein homodimerization activityFIPI 
peptide antigen bindingFNAS 
peptide antigen transportPTAS 
immune responsePIEA IEA IEA 
transportPIEA IEA IEA IEA 
protein complex assemblyPNAS 
antigen processing and presentation of endogenous peptide antigen via MHC class IPNAS 
intracellular protein transportPISS IMP IEA 
protein transportPIEA 
oligopeptide transportPIEA IEA IEA 
cytosol to ER transportPNAS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
immune system phenotypeMP#
hematopoietic system phenotypeMP#

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Leukocyte DisordersDIPI

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Antigen processing and presentation (04612)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
ABC transporters - General (02010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway