IpiRecord: IPI00122806

IPI00122806 - Cd4, ISOFORM 1 OF T-CELL SURFACE GLYCOPROTEIN CD4 PRECURSOR.
Uniprot Accession: Q61396
Uniprot ID: Q61396_MOUSE
Mapping: Chr 6, 124830325 - 124853807
Entrez Gene: 12504
Entrez MapView: Geneprod
MGI: MGI:88335
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4879)
Rat: Cd4, T-CELL SURFACE GLYCOPROTEIN CD4 PRECURSOR.
Mouse: Cd4, ISOFORM 1 OF T-CELL SURFACE GLYCOPROTEIN CD4 PRECURSOR.
Mouse: Cd4, ISOFORM 2 OF T-CELL SURFACE GLYCOPROTEIN CD4 PRECURSOR.
Mouse: Cd4, MUTANT T-CELL SURFACE GLYCOPROTEIN CD4.
Rat: Cd4, 51 KDA PROTEIN.
Rat: Cd4, 10 KDA PROTEIN.
Human: CD4, T-CELL SURFACE GLYCOPROTEIN CD4 PRECURSOR.
Human: CD4, 8 KDA PROTEIN.

Annotations for Cd4 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCIDA ISS IDA ISS ISS 
external side of plasma membraneCIEA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA ISS 
T cell receptor complexCNAS ISS ISS 
membraneCIEA IEA IEA 
integral to membraneCIEA RCA ISS IEA 
extracellular matrix structural constituentFNAS ISS 
glycoprotein bindingFIPI ISS 
transmembrane receptor activityFTAS ISS 
MHC class II protein bindingFNAS ISS ISS 
protein homodimerization activityFIDA ISS 
protein kinase bindingFIPI ISS 
zinc ion bindingFIDA ISS 
protein bindingFIPI 
coreceptor activityFNAS ISS 
positive regulation of peptidyl-tyrosine phosphorylationPIEA IDA ISS 
positive regulation of T cell activationPIEA IDA ISS 
cytokine productionPIEA IMP IGI 
T cell selectionPIDA ISS ISS ISS 
positive regulation of calcium-mediated signalingPIEA IDA ISS 
cell surface receptor linked signal transductionPIDA ISS 
immune responsePNAS IEA IEA ISS IEA 
cell adhesionPIEA IEA IEA 
T cell differentiationPISS 
T cell activationPIMP 
conjugation with cellular fusionPIDA ISS 
regulation of T cell activationPISS 
positive regulation of protein kinase activityPIDA ISS 
positive regulation of interleukin-2 biosynthetic processPNAS ISS ISS 
transmembrane receptor protein tyrosine kinase signaling pathwayPNAS ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn Un Un Un Un Un Un
lethality-postnatalMPUn
nervous system phenotypeMPUn
digestive/alimentary phenotypeMPUn
hematopoietic system phenotypeMPUn Un Un Un Un Un
life span-post-weaning/agingMPUn Un
no phenotypic analysisMPUn Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Antigen processing and presentation (04612)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cell adhesion molecules (CAMs) (04514)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Hematopoietic cell lineage (04640)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway