IpiRecord: IPI00123676

IPI00123676 - Abcb4, MULTIDRUG RESISTANCE PROTEIN 2.
Uniprot Accession: P21440
Uniprot ID: MDR2_MOUSE
Mapping: Chr 5, 8899723 - 8965232
Entrez Gene: 18670
Entrez MapView: Geneprod
MGI: MGI:97569
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4243)
Rat: Abcb4, MULTIDRUG RESISTANCE PROTEIN 2.
Mouse: Abcb4, MULTIDRUG RESISTANCE PROTEIN 2.
Mouse: Abcb4, MEMBER 4, FULL INSERT SEQUENCE (FRAGMENT).
Rat: Abcb4, 15 KDA PROTEIN.
Human: ABCB4, ATP-BINDING CASSETTE, SUBFAMILY B, MEMBER 4 ISOFORM C.
Human: ABCB4, ISOFORM 1 OF MULTIDRUG RESISTANCE PROTEIN 3.
Human: ABCB4, ISOFORM 2 OF MULTIDRUG RESISTANCE PROTEIN 3.

Annotations for Abcb4 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
intercellular canaliculusCIDA ISS 
membraneCIEA IEA 
cellular_componentCND 
integral to membraneCRCA ISS IEA 
membrane fractionCIDA 
apical plasma membraneCIDA 
Golgi membraneCIDA 
ATPase activity, coupled to transmembrane movement of substancesFIEA 
ATP bindingFIEA IEA IEA 
nucleoside-triphosphatase activityFIEA 
hydrolase activityFIEA IEA 
nucleic acid bindingFISS 
protein bindingFIPI IPI 
xenobiotic-transporting ATPase activityFIEA IEA 
nucleotide bindingFIEA IEA IEA 
ATPase activityFIEA IEA 
transportPIEA IEA IEA 
response to glucocorticoid stimulusPIEP 
response to drugPIEP 
response to xenobiotic stimulusPNAS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn
digestive/alimentary phenotypeMPUn
liver/biliary system phenotypeMPUn

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Cholestasis, IntrahepaticDISS
CholestasisDIEP
Diabetes Mellitus, ExperimentalDIED

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
multidrug resistance protein mediated transport pathwayWISS

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
ABC transporters - General (02010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway