IpiRecord: IPI00125726

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
peroxisome	C			IDA
cortical cytoskeleton	C		IDA	ISS IEA
perinuclear region of cytoplasm	C		IDA	ISS IEA
cytosol	C		TAS
nucleus	C			IDA
cytoplasm	C		IDA	ISS IDA IEA
nitric-oxide synthase activity	F	IEA	TAS	IDA TAS ISS IDA TAS
heme binding	F	IEA	NAS	TAS IEA
protein homodimerization activity	F		IDA	ISS IDA IEA
protein binding	F		IPI	ISS
amino acid binding	F			TAS
FAD binding	F	IEA	IEA	TAS IEA
electron carrier activity	F		IEA	IEA
iron ion binding	F	IEA	IEA IEA	IEA
NADP binding	F	IEA	IEA	TAS IEA
metal ion binding	F		IEA	IEA
zinc ion binding	F		IEA	IEA
oxidoreductase activity	F	IEA	IEA IEA
FMN binding	F	IEA	IEA	TAS IEA
calmodulin binding	F	IEA	TAS	IEA
cAMP-dependent protein kinase regulator activity	F			IDA
response to hypoxia	P		IDA	ISS IEA
cGMP-mediated signaling	P			IDA
nitric oxide biosynthetic process	P	IEA	IDA	IDA ISS IDA TAS
superoxide metabolic process	P		IMP	ISS ISS
protein kinase cascade	P			IMP
blood pressure regulation	P			IMP IMP
inflammatory response	P		TAS
defense response to bacterium	P		IMP	ISS
electron transport	P	IEA	IEA	IDA IEA
defense response to Gram-negative bacterium	P			IEP
signal transduction	P			IDA
regulation of heart contraction	P			IMP
blood vessel remodeling	P			IMP
endothelial cell proliferation	P			IEP
retinoic acid receptor signaling pathway	P			IEP
G-protein signaling, coupled to cGMP nucleotide second messenger	P			IDA
ovulation from ovarian follicle	P		IMP

Cellular Component

Biological Process

Molecular Function

Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
homeostasis/metabolism phenotype	MP		Un
immune system phenotype	MP		Un Un
vision/eye phenotype	MP		Un
normal phenotype	MP		Un
cardiovascular system phenotype	MP		Un Un
reproductive system phenotype	MP		Un
rheumatoid arthritis	N			QTM

Disease (9)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Shock, Hemorrhagic	D			IEP
Hypertension, Pulmonary	D			IEPISS
Demyelinating Diseases	D			IEP
Shock, Septic	D			IED
Coronary Arteriosclerosis	D			ISS
Aortic Aneurysm	D			IEP
Reperfusion Injury	D			IEPIEP
Aortic Aneurysm, Abdominal	D			IEP
Hypertension	D			IEPISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
arginine and proline metabolic pathway	W			IEA
endothelin signaling pathway	W			IEP

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Long-term depression (04730)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Calcium signaling pathway (04020)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Arginine and proline metabolism (00330)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway