IpiRecord: IPI00126078

IPI00126078 - Jak1, TYROSINE-PROTEIN KINASE JAK1.
Uniprot Accession: P52332
Uniprot ID: JAK1_MOUSE
Mapping: Chr 4, 100650299 - 100763214
Entrez Gene: 16451
Entrez MapView: Geneprod
MGI: MGI:96628
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5498)
Rat: Jak1, SIMILAR TO TYROSINE-PROTEIN KINASE JAK1.
Mouse: Jak1, TYROSINE-PROTEIN KINASE JAK1.
Mouse: Jak1, JANUS KINASE 1.
Mouse: Jak1, JANUS KINASE 1.
Human: JAK1, 133 KDA PROTEIN.
Human: JAK1, CDNA FLJ46518 FIS, CLONE THYMU3033630.
Human: JAK1, JANUS KINASE 1.

Annotations for Jak1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
membraneCIEA IEA IEA 
integral to membraneCIEA 
cytoskeletonCIEA IEA 
ATP bindingFIEA IEA IEA IEA 
nucleotide bindingFIEA IEA IEA 
protein-tyrosine kinase activityFIEA IDA ISS ISS IEA 
non-membrane spanning protein tyrosine kinase activityFIEA 
receptor activityFIEA 
growth hormone receptor bindingFIPI 
Janus kinase activityFIEA IEA 
protein bindingFIPI ISS 
kinase activityFIEA 
protein kinase activityFIEA 
transferase activityFIEA IEA IEA 
protein amino acid phosphorylationPIEA TAS IEA ISS IEA 
intracellular signaling cascadePIEA TAS IEA ISS 
peptidyl-tyrosine phosphorylationPIDA ISS 
cytokine and chemokine mediated signaling pathwayPIDA 
enzyme linked receptor protein signaling pathwayPIDA 
protein kinase cascadePIDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (5)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
behavior/neurological phenotypeMPUn
immune system phenotypeMPUn
lethality-embryonic/perinatalMPUn
hematopoietic system phenotypeMPUn
growth/size phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
Non-STAT, JAK dependent pathwayWISS
JAK-STAT signaling pathwayWTASISS

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Adipocytokine signaling pathway (04920)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Jak-STAT signaling pathway (04630)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayNot present in KEGG pathway