IpiRecord: IPI00132121

IPI00132121 - Egf, PRO-EPIDERMAL GROWTH FACTOR PRECURSOR.
Uniprot Accession: Q8VD07
Uniprot ID: Q8VD07_MOUSE
Mapping: Chr 3, 129669600 - 129747338
Entrez Gene: 13645
Entrez MapView: Geneprod
MGI: MGI:95290
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2831)
Rat: Egf, PRO-EPIDERMAL GROWTH FACTOR PRECURSOR.
Mouse: Egf, PRO-EPIDERMAL GROWTH FACTOR PRECURSOR.
Human: EGF, PRO-EPIDERMAL GROWTH FACTOR PRECURSOR.

Annotations for Egf and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCIEA IDA IDA ISS IEA 
nucleusCNR ISS 
membraneCIEA IEA IEA 
integral to membraneCIEA RCA ISS IEA 
extracellular regionCIC ISS 
plasma membraneCTAS ISS 
calcium ion bindingFIEA IEA IEA 
protein bindingFIPI ISS IEA 
epidermal growth factor receptor activating ligand activityFTAS ISS 
growth factor activityFIDA ISS ISS IEA 
epidermal growth factor receptor bindingFTAS 
branching morphogenesis of a tubePIEA IDA ISS IEA 
positive regulation of mitosisPIDA 
protein kinase cascadePTAS 
positive regulation of epidermal growth factor receptor activityPIDA 
regulation of peptidyl-tyrosine phosphorylationPIEA IDA ISS IEA 
peptidyl-tyrosine phosphorylationPIDA ISS 
positive regulation of granule cell precursor proliferationPIEA IDA IEA 
chromosome organization and biogenesis (sensu Eukaryota)PTAS ISS 
angiogenesisPIDA 
regulation of protein secretionPIMP 
DNA replicationPTAS ISS 
positive regulation of cell proliferationPIGI ISS IDA IDA IGI IGI ISS ISS 
epidermal growth factor receptor signaling pathwayPIEA IDA IGI ISS ISS IEA 
activation of MAPKK activityPIEA IDA ISS IEA 
positive regulation of phosphorylationPIDA 
activation of MAPK activityPTAS ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMP#
endocrine/exocrine gland phenotypeMP#
immune system phenotypeMP#
touch/vibrissae phenotypeMP#
vision/eye phenotypeMP#
digestive/alimentary phenotypeMP#
normal phenotypeMP#
reproductive system phenotypeMP#
growth/size phenotypeMP#

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
epidermal growth factor/neuregulin signaling pathwayWIDA

KEGG Pathway (7)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway