IpiRecord: IPI00132969

IPI00132969 - Psenen, GAMMA-SECRETASE SUBUNIT PEN-2.
Uniprot Accession: Q9CQR7
Uniprot ID: PEN2_MOUSE
Mapping: Chr 4, 40963930 - 40964235
Entrez Gene: 66340
Entrez MapView: Geneprod
MGI: MGI:1913590
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_450)
Rat: Psenen, LRRGT00140.
Mouse: Psenen, GAMMA-SECRETASE SUBUNIT PEN-2.
Human: PSENEN, GAMMA-SECRETASE SUBUNIT PEN-2.

Annotations for Psenen and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to plasma membraneCIDA 
integral to membraneCRCA 
Golgi apparatusCIDA IEA 
endoplasmic reticulumCIDA IEA 
membraneCIEA IEA 
protein bindingFIPI IPI 
amyloid precursor protein catabolic processPTAS 
membrane protein ectodomain proteolysisPIDA 
Notch receptor processingPTAS 
protein processingPIDA 
positive regulation of enzyme activityPIDA 
Notch signaling pathwayPIEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (1)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
lethality-postnatalMP#

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Alzheimer's disease (05010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Notch signaling pathway (04330)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway