IpiRecord: IPI00133537

IPI00133537 - Cdkn1b, CYCLIN-DEPENDENT KINASE INHIBITOR 1B.
Uniprot Accession: Q4FJM2
Uniprot ID: Q4FJM2_MOUSE
Mapping: Chr 6, 134886110 - 134890000
Entrez Gene: 12576
Entrez MapView: Geneprod
MGI: MGI:104565
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5066)
Rat: Cdkn1b, P27 KIP1.
Mouse: Cdkn1b, CYCLIN-DEPENDENT KINASE INHIBITOR 1B.
Mouse: Cdkn1b, CLONE:B430307G09 PRODUCT:CYCLIN-DEPENDENT KINASE INHIBITOR 1B.
Mouse: Cdkn1b, SEQUENCE.
Human: CDKN1B, CYCLIN-DEPENDENT KINASE INHIBITOR 1B.
Human: CDKN1B, 12 KDA PROTEIN.
Human: CDKN1B, 23 KDA PROTEIN.

Annotations for Cdkn1b and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytosolCIEA IDA 
cytoplasmCIDA IDA ISS ISS 
nucleusCIDA IEA IDA IDA ISS ISS IEA 
kinase activityFIEA IEA 
protein bindingFIPI IPI IPI IPI IPI IPI IPI IPI IPI IPI IPI IPI ISS ISS 
protein kinase inhibitor activityFIEA 
cyclin-dependent protein kinase inhibitor activityFTAS IEA IDA IDA ISS ISS IEA 
transforming growth factor beta receptor, cytoplasmic mediator activityFTAS ISS 
negative regulation of cyclin-dependent protein kinase activityPIEA IDA ISS 
inner ear developmentPIEA IMP 
potassium ion transportPIGI 
cell cycle arrestPIMP IEA IDA ISS ISS IEA 
negative regulation of cell proliferationPIMP ISS ISS 
cell cyclePIEA IEA 
negative regulation of cell motilityPIEA IDA ISS 
regulation of cyclin-dependent protein kinase activityPISS 
positive regulation of cell proliferationPIEA IMP ISS 
positive regulation of microtubule polymerizationPIEA IGI ISS 
sensory perception of soundPIEA IMP 
negative regulation of epithelial cell proliferationPIEA IMP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (22)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
craniofacial phenotypeMPUn
cellular phenotypeMPUn
behavior/neurological phenotypeMPUn Un Un
endocrine/exocrine gland phenotypeMPUn Un Un
homeostasis/metabolism phenotypeMPUn Un Un
immune system phenotypeMPUn Un Un Un
lethality-embryonic/perinatalMPUn
lethality-postnatalMPUn
muscle phenotypeMPUn
nervous system phenotypeMPUn Un Un
respiratory system phenotypeMPUn
vision/eye phenotypeMPUn Un
tumorigenesisMPUn Un Un Un Un
digestive/alimentary phenotypeMPUn
cardiovascular system phenotypeMPUn
hematopoietic system phenotypeMPUn Un Un Un
reproductive system phenotypeMPUn Un Un
no phenotypic analysisMPUn
liver/biliary system phenotypeMPUn
pigmentation phenotypeMPUn
growth/size phenotypeMPUn Un Un Un Un
life span-post-weaning/agingMPUn Un Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cell cycle (04110)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway