IpiRecord: IPI00133840

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
cytoplasm	C			IDA
protein kinase inhibitor activity	F	TAS		ISS
protein binding	F	IEA	IPI IPI	ISS IEA
response to peptide hormone stimulus	P			IEP
response to bacterium	P			IEP
JAK-STAT cascade	P	TAS		TAS IDA ISS
response to heat	P			IEP
negative regulation of insulin receptor signaling pathway	P	IEA	IDA	ISS IEA
response to gamma radiation	P			IEP
protein kinase cascade	P			IDA
regulation of cell growth	P	IEA	IEA	TAS IEA
response to insulin stimulus	P			IEP
intracellular signaling cascade	P	IEA	IEA	IEA
response to hypoxia	P			IEP
negative regulation of signal transduction	P		IEA
anti-apoptosis	P	TAS		ISS
response to food	P			IEP
regulation of protein amino acid phosphorylation	P	IEA	IDA	ISS IEA
signal transduction	P			TAS IDA
response to drug	P			IEP
aging	P			IEP

Cellular Component

Biological Process

Molecular Function

Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
adipose tissue phenotype	MP		Un
behavior/neurological phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un
lethality-embryonic/perinatal	MP		Un
immune system phenotype	MP		Un Un Un
hematopoietic system phenotype	MP		Un Un
growth/size phenotype	MP		Un

Disease (10)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Obesity	D			ISS
Fatty Liver	D			ISS
Insulin Resistance	D			ISS
Fibrosis	D			IEP
Status Epilepticus	D			IEP
Helicobacter Infections	D			IEP
Arthritis, Experimental	D			IEP
Burns	D			IEP
Endotoxemia	D			IEP
Reperfusion Injury	D			IED

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
leptin system pathway	W			ISS
insulin signaling pathway	W			ISS
JAK-STAT signaling pathway	W			ISS

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Adipocytokine signaling pathway (04920)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Type II diabetes mellitus (04930)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Insulin signaling pathway (04910)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway