IpiRecord: IPI00135708

IPI00135708 - Map2k2, DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2.
Uniprot Accession: Q63932
Uniprot ID: MP2K2_MOUSE
Mapping: Chr 10, 80509092 - 80527465
Entrez Gene: 26396
Entrez MapView: Geneprod
MGI: MGI:1346867
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6761)
Rat: Map2k2, DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2.
Mouse: Map2k2, DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2.
Mouse: Map2k2, KINASE 2, FULL INSERT SEQUENCE.
Mouse: Map2k2, FULL INSERT SEQUENCE.
Mouse: Map2k2, MITOGEN ACTIVATED PROTEIN KINASE KINASE 2.
Rat: Map2k2, 27 KDA PROTEIN.
Human: MAP2K2, DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2.
Human: MAP2K2, 34 KDA PROTEIN.

Annotations for Map2k2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular regionCNAS 
transferase activityFIEA IEA IEA 
ATP bindingFNAS IEA IEA IEA IEA 
protein serine/threonine kinase activityFNAS IEA IEA IEA IEA 
protein bindingFIPI 
kinase activityFIEA 
protein-tyrosine kinase activityFIEA IEA IEA 
protein kinase activityFIEA 
nucleotide bindingFIEA IEA IEA 
protein amino acid phosphorylationPNAS IEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMP#
craniofacial phenotypeMP#
homeostasis/metabolism phenotypeMP#
lethality-embryonic/perinatalMP#
vision/eye phenotypeMP#
digestive/alimentary phenotypeMP#
normal phenotypeMP#
hearing/vestibular/ear phenotypeMP#
growth/size phenotypeMP#

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
The extracellular signal-regulated RAF/MEK/ERK pathwayWNASIMP

KEGG Pathway (13)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
GnRH signaling pathway (04912)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term depression (04730)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Insulin signaling pathway (04910)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term potentiation (04720)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway