IpiRecord: IPI00136814

IPI00136814 - Bdkrb2, ISOFORM LONG OF B2 BRADYKININ RECEPTOR.
Uniprot Accession: P32299-1
Uniprot ID: BKRB2_MOUSE
Mapping: Chr 12, 105964222 - 105994121
Entrez Gene: 12062
Entrez MapView: Geneprod
MGI: MGI:102845
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6534)
Rat: Bdkrb2, ISOFORM SHORT OF B2 BRADYKININ RECEPTOR.
Mouse: Bdkrb2, ISOFORM LONG OF B2 BRADYKININ RECEPTOR.
Mouse: Bdkrb2, ISOFORM SHORT OF B2 BRADYKININ RECEPTOR.
Rat: Bdkrb2, ISOFORM LONG OF B2 BRADYKININ RECEPTOR.
Human: BDKRB2, ISOFORM LONG OF B2 BRADYKININ RECEPTOR.
Human: BDKRB2, ISOFORM SHORT OF B2 BRADYKININ RECEPTOR.

Annotations for Bdkrb2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCISS IDA 
membraneCIEA 
integral to plasma membraneCISS 
integral to membraneCRCA ISS 
purinergic nucleotide receptor activity, G-protein coupledFRCA ISS 
G-protein coupled receptor activityFIEA 
protein bindingFIDA IDA IDA 
rhodopsin-like receptor activityFIEA 
phosphoinositide phospholipase C activityFISS 
receptor activityFIEA 
bradykinin receptor activityFRCA IDA ISS ISS 
signal transducer activityFIEA 
G-protein coupled receptor protein signaling pathwayPIEA IEA ISS 
smooth muscle contractionPISS 
negative regulation of cell proliferationPIMP 
inflammatory responsePISS 
circulationPISS 
signal transductionPIEA 
negative regulation of blood pressurePIMP 
sensory perception of painPTAS 
elevation of cytosolic calcium ion concentrationPISS IMP 
sensory perceptionPISS 
transmembrane receptor protein tyrosine kinase signaling pathwayPISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (12)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
cellular phenotypeMPUn
adipose tissue phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
homeostasis/metabolism phenotypeMPUn Un
life span-post-weaning/agingMPUn Un
reproductive system phenotypeMPUn
renal/urinary system phenotypeMPUn Un
digestive/alimentary phenotypeMPUn
normal phenotypeMPUn
skeleton phenotypeMPUn
increased blood pressureNIED

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Myocardial IschemiaDIED
HypertensionDIED

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Neuroactive ligand-receptor interaction (04080)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Calcium signaling pathway (04020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Complement and coagulation cascades (04610)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway